Postlab quiz 5 Flashcards
What is a neuron refered to as (video)
multipolar neuron (normal)
What is used in the video to dtermine resting membrane potential
electrode attached to voltmeter
What instrument did we use in lab
ocilloscope
depolarization =
stimulation
hyper polarization =
inhibition
RMP in podcast
-65 to -95mV
What is distrurbed when stimulus takes place
RMP
Na+ channels: The channel is closed at this point
RMP
Na+ channels: The channel is opened by this
depolarization (AP)
Na+ channels: the channel is inativiated during this period
refractory period (absolute)
Na+ channels: How is the channel inactivated
opening blocked by protein
Na+ channels: These are this type of channel
voltage gated
What opens voltage gated channels
ambient voltage
when is threshold
-50 mV
What is the top of the spike in the podcast
+30Mv
What resets RMP
Na/K pumps
milliseconds per AP
4 mS
AP frequency is determined by
strength of stimulus
Strong stimuli are felt more strongly because of this
the rate/frequency of the AP
During an absolute RP this occurs
inactivation of Na+ channels
During a relative Rp this occurs
hyperpolarizaition due to efflux of K+
This is needed to generate a AP during relative RP
greater than normal strength of stimulus
These types of neurons are mylinated
motor
sensory
rate of impulse conduction mylinated vs unmylinated
300 m/s to 1 m/s
Spatial summation:
occurs when excitatory potentials from many different presynaptic neurons cause the postsynaptic neuron to reach its threshold and fire.
Temporal summation:
occurs when a single presynaptic neuron fires many times in succession, causing the postsynaptic neuron to reach its threshold and fire.
unidirectional propagation
AP can only move in one way due to absolute refractory period (can move in either way to start)
Chronaxie time
minimum time required for electrical current that is 2x the strength of the rheobase to stimulate neuron
What does chronaxie time measure
excitability
rheobase voltage
lowest intensity which just stimulated nerves
Axis of the graph shown in lab-lec
Y = stimulus strength X = time
Shape of line on the graph shown in lab-lec
exponentially flattening negative slope
What are the names of the two strength of stimulus lines on the graph shown in lab-lec (bottom-top)
Rheobase
Chronaxie
What does temporal summation allow
allows for the post-synaptic neuron to reach threshold faster
chronaxie time is dependent on this
density of voltage gated Na+ channels on a cell
Temporal summation uses this to generate a response in the post-synaptic cell
high frequency AP that overlap and summate with each other
temporal summation is generated by this many neurons
1
spatial summation is generated by this many neurons
many
These are examples of excitable cells
neurons
muscles
T/F: some synaptic transmissions are inhibitory
T, post-synaptic cell is hyperpolarized
open ligand gated K+ channels
Two major physiologic properties of neurons
irritability
conductivity
Irritability is
the ability to respond to stimuli and conver them into nerve impulses
conductivity is
the ability to transmit an impulse
This establishes RMP
Na+/K+ pumps
These are the main cause of the negative charge inside of the cell
intracellular proteins
The AP follows this law
All-or-none law
For this lab we would have used these two tools
electronic stimulator
oscilloscope
The action potential on the screen reflects this
the action potentials of many neurons in the nerve bundle
T/F: all of the neurons are always stimulated if an action potential is generated
F
How does mechanical stimulation create an action potential
pressure opens Na+ channels which begins depolarization of the cell
How does thermal stimulation create an action potential
Increases kinetic energy in ions allowing for faster diffusion