Polycystic Kidney Disease Flashcards
1
Q
What is PKD?
A
A genetic condition where kidney tissue is replaced with fluid-filled cysts
1
Q
What are the 2 genes affected in ADPKD?
A
- PKD1 chromosome 16 - most common
- PKD2 chromosome 4
2
Q
What are complications of ADPKD?
A
- Chronic pain
- HTN
- Gross haematuria
- Recurrent UTI
- Renal stones
3
Q
How is ADPKD managed?
A
- Tolvaptan can slow the development of cysts
- Anti-HTN
- Analgesia
- Abx
- Dialysis/Transplant for end stage renal failure