Focal Segmental Glomerulosclerosis Flashcards
1
Q
What is focal segmental glomerulosclerosis?
A
A cause of nephrotic syndrome and CKD common in renal transplant patients
2
Q
What causes FSG?
A
- Idiopathic
- Secondary to other renal pathology
- HIV
- Heroin
- Alport syndrome
3
Q
How is FSG investigated?
A
Renal Biopsy - focal and segmental sclerosis on light microscopy and effacement of foot processes on electron microscopy
4
Q
How is FSG managed?
A
Steroids and immunosuppressants (cyclosporine, tacrolimus or rituximab)
