Polifarmacia Flashcards

1
Q

Define polifarmacia

A
  • Menor ≤ 3 fármacos

- Mayor ≥ 5 fármacos

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2
Q

Cambios en TFG adulto mayor

A

⬇️

1% año a partir de los 40 años

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3
Q

fármacos hidrosolubles que tienen menor distribución = aun nivel serico

A

Digoxina, gentamicina, teofilina

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4
Q

fármacos liposolubles que tienen mayor distribución

A

= aun vida media

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5
Q

BZD que vida media usamos? y cual es su antídoto

A

accionarial corta e intermedia

flumazenial

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6
Q

fármacos dan hipoalbunemia

A

azetazolamida
BZD
warfarin
AAS y AINES

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7
Q

Alt metabolica del adulto mayor

A

⬇️ flujo hepático

⬇️ masa hepática

⬇️ inducción enzimática

Metabolismo más lento

⬆️ de vida media

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8
Q

regla Cockroft

A

[ (140-edad/peso kg) / CrS ] x 72

mujeres resultado x 0.85

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9
Q
Cambios del farmaco debido envejecimiento 
DIazepam 
Furosamida 
Morfina
verapamilo 
warfarin
A
DIazepam ⬆️ sedación 
Furosamida ⬇️ resp diuretica 
Morfina⬆️ analgesia 
verapamilo ⬆️  efecto anti HAS 
warfarin  ⬆️  efecto anticoagulante
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10
Q

E.A DIURETICOS

H3, H, E

A
Hipokalemia
Hipotensión
Hiponatremia
Hiperazotemia
Estreñimiento
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11
Q

E.A B BLOCK

A

Bloqueos AV
Broncoespasmo EPOC
Depresión
Hiperglucemia

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12
Q

E.A IECA

A

Perder efecto con AINEs
Angiodema
tos seca
HiperCa

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13
Q

E.A Ca antagonista

A

Edema perimaleolar

cefalea

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14
Q

E.A ARA II

A

Hiper Ca

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15
Q

E.A AINE

A

Irritación gástrica

Intoxicación renal

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16
Q

E.A Acetaminofen

A

Daño hepático

17
Q

E.A Opiodes

A

Confusión
PERDIDA MEMORIA
delirium

18
Q

E.A BZD

A

Alteración memoria

delirium

19
Q

Psicotrópicos

A
Ganacia de peso 
Caidas
hiponatremi
manifestaciones extrapirimidales 
hiperglicemia
prolonga QT
Efectos parkinsonianos