Plasma Specialization

Question 1

3 types of apical projection

Answer 1

Microvilli, stereocilia, cilia

Question 2

Microvilli function and structure

Answer 2

Projection of plasma membrane. Contains MF, surrounded by glycocalyx. Increase surface area

Question 3

Stereocilia structure and function

Answer 3

Contain MF. In ear and epididymis

Question 4

Cilia

Answer 4

Motile to move extracellular materiel. Contain axoneme

Question 5

Flagella

Answer 5

Only in sperm. Mitochondria around basal body

Question 6

Zonulae occludentes

Answer 6

Tight junctions. Near apical surface, encircle it. Junctions from three proteins

Question 7

Proteins in tight junctions

Answer 7

Claudins, occludin, JAM.

Also ZO 1,2,3

Question 8

Zonula adherens

Answer 8

Just underneath occluding junctions. Cadherins bind actin underneath by catenins cell. Need calcium.

Question 9

Desmosome

Answer 9

Desmoproteins bind IF and two cells together. Plaque junctions.

Question 10

Gap junction

Answer 10

Circular patches of connexin. 6 molecules form channel, several hundred patches form junction. Allow cyto connection

Question 11

Focal contacts

Answer 11

Transmembrane integrins bind ECM molecules. Uses actin and talin.

Question 12

Hemidesmosomes

Answer 12

Like desmo, but anchor IF to ECM. Plectin, Erbin, BP230. Anchor to basal lamina