Mitochondria Flashcards
Mitochondria cell volume
22%, 1700 per cell.
Are mitochondria associated with microtubules
Yes
Mitochondria structure
Outer membrane, intracristal space, inner membrane, matrix.
Outer membrane
Permeable to small molecules, contains porins.
Matrix
Contains Krebs cycle. Slightly higher pH
Inner membrane
Has electron transport chain. Pumps hydrogen from matrix to membrane space. Makes electrochemical gradient
ATP synthase speed
100 ATP/sec. turns electrochemical to mechanical.
ATP antiporter
ATP out ADP in. Driven by electron gradient.
Brown fat mitochondria
In infants. Makes heat instead of ATP. Used thermogenin
Other mitochondria functions
Apoptosis, calcium, aging
How do proteins enter mitochondria
Unfolded, passed through, cleaved, remolded.
Mitochondria dna
Circular, UGA isn’t stop codon. Own genetic code
Peroxisomes
Most in liver and kidney. Degrades toxins, oxidates fatty acids.
Peroxisome contents
Oxidase and catalase.
Heteroplasmic
Mixture of normal and mutant mitochondria