Cytoskeleton

Question 1

Fiber basics

Answer 1

Have polymerized and un in cytosol. MT and MF are polar. Can assemble and disassemble. Fill cell, important in mitosis (anaphase)

Question 2

Microtubule structure

Answer 2

Hollow rods. 13 protofilaments made of a/b dimers

Question 3

Centrosome function

Answer 3

Nucleates and organizes MT array. 2 centrioles that can divide, minus end of fibers here.

Question 4

Centriole structure

Answer 4

Triplet structured microtubules

Question 5

MAPs

Answer 5

Microtubule associated proteins, bind to and enhance MTs

Question 6

Motor protein direction

Answer 6

Dynein minus, kinesin plus

Question 7

Flagella and cillia

Answer 7

Whip like movements, formed of MT network.

Question 8

Axoneme

Answer 8

Inner core. Central pair of MT, 9 pairs around two. Has radial spoke proteins, with dynein attached to one doublet.

Question 9

Primary cillia

Answer 9

Sensory structures

Question 10

Microfilaments

Answer 10

Twisted pair of filaments. Actin monomers. On inner plasma membrane. Contractile ring. Myosin associated

Question 11

IF keratin

Answer 11

Epithelial

Question 12

IF desmin

Answer 12

Muscle

Question 13

IF vimentin

Answer 13

Mesenchymal

Question 14

GFAP IF

Answer 14

Neural astrocytes

Question 15

Peripherins IF

Answer 15

Neurons

Question 16

Lamins IF

Answer 16

Nuclear envelope

Question 17

Neurofilaments

Answer 17

Neurons

Question 18

Desmoplakin

Answer 18

Cell to cell junctions

Question 19

BP 230 function?

Answer 19

Connect IF to epithelial

Question 20

Filaggrin function?

Answer 20

Bundles keratin

Question 21

IF functions

Answer 21

Maintain nucleus position, size of large axons, integrity of cells, part of skin and hair.

Question 22

Size relative

Answer 22

MT big, IF middle, MF low