Physiology_Lesson_2_-_Reflexes-Blood_Physiology_Batch_2024 Flashcards
Which types of WBCs are formed in lymphogenous tissue?
A. Neutrophils
B. Lymphocytes
C. Monocytes
D. Platelets
B. Lymphocytes
Which types of WBCs are formed and mature in the bone marrow?
A. Neutrophils
B. Lymphocytes
C. Plasma cells
D. None of the above
A. Neutrophils
The first cell that can be identifies as belonging to the erythroblast series;
A. Basophil erythroblast
B. Polychromatophil erythroblast
C. Orthochromatic erythroblast
D. Proerythroblast
A. Basophil erythroblast
What is the first step in neutrophil invasion?
A. Intercellular attachment loosens, neutrophils crawl through spaces
B. Release of inflammatory cytokines by inflamed tissues
C. Neutrophils crawl toward injured tissues
D. Adhesion molecules re
A. Intercellular attachment loosens, neutrophils crawl through spaces
What is the advantage of a biconcave disc shape?
A. Deformable
B. Unbreakable
C. Stretchable
D. Modifiable
A. Deformable
Which of the following statements describe the relationship of acquired immunity and lymphocytes?
A. Acquired immunity is the product of lymphocytes
B. Acquired immunity may proceed with genetic lack of lymphocytes
C. Acquired immunity will develop without lymphocytes
D. All of the above
A. Acquired immunity is the product of lymphocytes
Which of the following are the highlights of a phagocytosis by neutrophils:
A. Neutrophils enter the tissues as immature cells, unable to begin phagocytosis.
B. Neutrophils mature in tissues then approach a particle to be phagocytized.
C. Neutrophils first projects pseudopodia, then attaches itself
D. A single neutrophil can ingest 3-20 bacteria before inactivation.
D. A single neutrophil can ingest 3-20 bacteria before inactivation.
The most common form of hemoglobin in an adult human being is a combination of:
A. Two alpha chains and two gamma chains
B. Two alpha chains and two beta chains
C. Two alpha chains and two delta chains
D. Two beta chains and two delta chains
B. Two alpha chains and two beta chains
Objectives of pre-processing of lymphocytes include the following, except:
A. Pre-processing adds capability to lymphocyte stem cells to form activated T lymphocytes or antibodies.
B. Lymphocytes develop extreme diversity for reacting to different specific antigens.
C. Pre-processing makes certain that lymphocytes will react on the antigens and proteins present in the body’s own tissues.
D. Pre-processed cells react against antigen from transplanted tissue from another person.
C. Pre-processing makes certain that lymphocytes will react on the antigens and proteins present in the body’s own tissues.
Functions of the Monocyte-Macrophage system are following, except;
A. Lymph nodes have small numbers of macrophages that they partially prevent particle dissemination in the body
B. The spleen is the next line of defense if the organism enter the circulation
C. Kupffer cells prevent invasion from the gastrointestinal tract
D. Alveolar macrophages form giant cell capsule for indigestible particles
A. Lymph nodes have small numbers of macrophages that they partially prevent particle dissemination in the body
Which of the following statements is true of the hemoglobin molecule?
A. Synthesis of hemoglobin occurs and ends in the proerythroblast stage.
B. A hemoglobin chain is a subunit of hemoglobin and four chains form the hemoglobin molecule.
C. Each hemoglobin molecule contains one atom of iron which binds with one molecule of oxygen.
D. The binding affinity of hemoglobin to oxygen is independent of the type of hemoglobin chain.
B. A hemoglobin chain is a subunit of hemoglobin and four chains form the hemoglobin molecule.
Growth and reproduction of the different stem cells are controlled by the following factors causing increased rate of production, except;
A. High altitudes
B. Prolonged cardiac failure
C. Hyperventilation
D. Infectious diseases
C. Hyperventilation
Adaptive immunity consist of the following features
A. Formation of large numbers of lymphocytes B. Phagocytosis of bacteria by macrophages
B. Destruction of organisms by digestive enzymes
D. All of the above
A. Formation of large numbers of lymphocytes
The following are true statements of the genesis of red blood cells, except:
A. As the PHSC reproduce, all cells differentiate to form the circulating cell types.
B. A small portion of PHSC remains exactly like the original to maintain supply.
C. PHSC are retained in the bone marrow, inside their numbers decline with age
D. PHSC are very much like the intermediate-stage stem cells but have committed to a particular line of cells.
A. As the PHSC reproduce, all cells differentiate to form the circulating cell types.
After approximately 120 days, RBCs burst and release their hemoglobin which is phagocytize in the:
A. Liver
B. Spleen
C. Bone marrow
D. All of the above
D. All of the above
The mechanisms by which the body recognizes invasion:
A. Proteins that have a small molecular weight B. Epitopes on surfaces of large molecules
B. Toxins with the same chemical compounds as the body’s cells
D. All of the above
B. Epitopes on surfaces of large molecules
Which of the following secretes antibodies that are reactive agents against foreign antigens?
A. T cytotoxic lymphocytes
B. T helper lymphocytes
C. T suppressor lymphocytes
D. B lymphocytes
D. B lymphocytes
In an atmosphere of low O2, which of the following will occur?
A. Erythropoietin forms after 24 hours.
B. Red blood cells appears in the circulation within 5 days
C. EPO causes proerythroblast to pass more rapidly through different stages
D. Few RBCs are formed by the bone marrow
C. EPO causes proerythroblast to pass more rapidly through different stages
Which of the following have the greatest diversity?
A. T cytotoxic lymphocytes
B. T helper lymphocytes
C. T suppressor lymphocytes
D. B lymphocytes
B. T helper lymphocytes
After the age of 20 years, RBCs are produced by which of the following?
A. Vertebrae
B. B. Humerus
C. Femur
D. Liver
A. Vertebrae
Which of the following combination is correct? A. Bone marrow dysfunction - aplastic anemia B. Rapid haemorrhage - megaloblastic anemia C. RBC abnormalities - idiopathic aplastic anemia
D. Vitamin B12 deficiency - idiopathic aplastic anemia
A. Bone marrow dysfunction - aplastic anemia
Inflamed tissues releases cytokines which causes endothelial cells to secrete selectins and ICAM-1 which reacts with neutrophils’ integrin causing adhesion:
A. Diapedesis
B. Margination
C. Chemotaxis
D. Phagocytosis
B. Margination
Monocytes in the Reticuloendothelial system are described as:
A. Monocytes attached to tissues for months or years
B. Monocytes perform specific local function in tissues
C. Once activated Monocytes break off and enlarge to be come macrophages
D. All of the above
D. All of the above
Chemical substances that may function as chemotactic signals:
A. Degenerative tissue product
B. Activated complement complex
C. Products caused by plasma clotting
D. All of the above
D. All of the above
The following statements characterized macrophages, which statement is not true?
A. End- stage product of monocytes.
B. Capable of ingesting a hundred bacteria.
C. They are able to engulf only small particles. D. Does not get inactivated after phagocytosis.
C. They are able to engulf only small particles
Bone marrow produces few WBC?
A. Leukemia
B. Leukopenia
C. Lymphoma
D. Leukocytosis
B. Leukopenia
Which of the following is/are responsible for humoral immunity?
A. T cytotoxic lymphocytes
B. T helper lymphocytes
C. T suppressor lymphocytes
D. B lymphocytes
D. B lymphocytes
Which of the following are examples of acquired immunity?
A. Immunization
B. Non-IgE allergy
C. Asthma
D. Parasitism
A. Immunization
When iron (Fe++) combines with a beta globulin in the blood plasma and transported to tissue cells:
A. Ferritin
B. Transferrin
C. Apotransferrin
D. Apoferritin
B. Transferrin
What are the responses of neutrophils and macrophages to acute bacterial infection?
A. Within minutes of infection, tissue macrophages provide the first line of defense. B. Within the 1 hour, second macrophage invasion due to monocytes from the blood entering the tissues provides the 2nd line of defense.
B. Several days later, neutrophilia occurs, providing the 3rd line of defense.
D. Formation of pus is the 4th line of defense.
A. Within minutes of infection, tissue macrophages provide the first line of defense
Undifferentiated cells in leukemia would mean? A. The cancerous process is more chronic
B. The disease is developing slowly
C. The cancerous process is acute
D. Some are functional, providing normal protection
C. The cancerous process is acute
Which type of WBC has the longest life span?
A. Neutrophils
B. Lymphocytes
C. Basophils
D. Platelets
B. Lymphocytes
What are the roles of Vitamin B12 and Vitamin B9, in the development of RBCs?
A. Lack of these cause failure to proliferate rapidly.
B. Essential for the synthesis of RNA.
C. Significant with rate but not with maturation. D. Abundance of Vit. B12 and B9 causes macrocytes
A. Lack of these cause failure to proliferate rapidly
The following statements describe eosinophils, except:
A. Produced in large numbers in humans with parasitic infections.
B. Most parasites are phagocytize by eosinophils
C. Eosinophils attach to juvenile forms and release major basic protein.
D. Eosinophils migrate towards inflamed allergic tissues.
B. Most parasites are phagocytize by eosinophils
Which of the following statement best describe the relationship between Vitamin B12 and intrinsic factor, except;
A. Intrinsic factor gives vitamin B12 protection from digestion from gastrointestinal secretion. B. Lack of intrinsic factor causes faulty absorption of the vitamin B12.
C. Vitamin B12 is transported with intrinsic factor through the brush border membranes in the ileum.
D. A few days of defective B12 absorption will cause maturation failure anemia.
D. A few days of defective B12 absorption will cause maturation failure anemia.
Aside from hypoxia, other sensors that send signal to the kidneys to produce erythropoietin include which one?
A. Cytokines
B. Bradykinins
C. Prostaglandins
D. Acetylcholine
B. Bradykinins
. Directly attacks and destroy bacteria, viruses and other injurious agents:
A. Neutrophils
B. Lymphocytes
C. Plasma cells
D. Platelets
A. Neutrophils
Of the total white blood cells, which type has the highest percentage?
A. Neutrophils
B. Lymphocytes
C. Basophils
D. Eosinophils
A. Neutrophils
The following are the roles by which macrophages activates T lymphocytes and B lymphocytes
A. They phagocytize and partially digest invading organisms.
B. Antigenic products are liberated in the macrophage cytosol.
C. Pass the antigens via direct cell to cell contact directly to lymphocytes.
D. Secretion of Interleukin-1 is in essential for further growth and reproduction of lymphocytes.
D. Secretion of Interleukin-1 is in essential for further growth and reproduction of lymphocytes
Which of the following best describes the human body’s innate Immunity?
A. Develop after the body is first attack by bacteria, viruses or toxins.
B. Often weeks or months are required for the immunity to develop.
C. Powerful and specific response to an individual invading agent.
D. Presence in the blood of certain substances and cells that attaches to foreign organisms and destroy them.
D. Presence in the blood of certain substances and cells that attaches to foreign organisms and destroy them.