Physiology_Lesson_1_-_Principles_of_Cell_Function-Muscle_Feed_Batch_2026 Flashcards
- Following the principles of osmosis, if a cell were to be placed in a hypertonic solution, what will be the most likely effect?
A. Water moves from outside to inside of a cell
B. Water moves from inside to outside of the cell
C. Water moves freely in and out of the cell with no change in cell volume
D. There will be no net movement of water in the 2 compartments
B. Water moves from inside to outside of the cell
- Oxygen and carbon dioxide enter and leave the cell through which mechanism?
A. Active transport
B. Facilitated diffusion
C. osmosis
D. simple diffusion
D. simple diffusion
- Which of the following components of cell membrane function as ion channels and carriers?
A. Carbohydrates
B. Cholesterol
C. lipids
D. proteins
D. proteins
- The primary determinant of plasma osmolarity is;
A. Calcium
B. Chloride
C. potassium
D. sodium
D. sodium
- For osmosis to occur, a semipermeable membrane must be present which is permeable to:
A, Both solvent and solute
B.The solvent but not the solute
C. the solute but not the solvent
D. neither solvent nor solute
B.The solvent but not the solute
- Tissues capable of oxidative phosphorylation or are metabolically active have high amounts of which of the following organelles?
A. Endoplasmic reticulum
B. Golgi apparatus
C. lysosomes
D. mitochondria
D. mitochondria
- Which of the following IS LOW in ECF?
A. Calcium
B. Chloride
C. glucose
D. sulfates
sulfates
- Percentage of body water is HIGHEST in which of the following?
A. Adult male
B. Obese female
C. newborn
D. elderly senior citizen
C. newborn
- Intracellular fluid is how many percent of body weight?
A. 20
B. 40
C. 60
D. 80
B. 40
- Water will move from ECF to ICF if cells are suspended in this solution:
A. Hypertonic solution
C. Isotonic solution
B. Hypotonic solution
D. all of these
B. Hypotonic solution
- Movement of fluid between ECF and ICF is influenced by:
A. Concentration of water molecules
B. Filtration pressure
C. Osmotic pressure differences
D. Presence of aquaporins
C. Osmotic pressure differences
- In the Gibbs-Donnan effect, the impermeant molecule that attracts osmotically active
particles into the intracellular compartment is:
A. Chloride
B. Potassium
C. proteins
D. sodium
C. proteins
- During instances of cell shrinking. the cell regulates its volume by:
A. Reducing the number of aquaporins
B. Transporting osmotically active particles out of the cell
C. Inhibition of Na+-KATPase activity
D. Rapid uptake of osmotically active particles into the cell
D. Rapid uptake of osmotically active particles into the cell
- Changes in the levels of one of the following ions can affect membrane voltage because of
the great conductance of the cell membrane to:
A. Calcium
B. Chloride
C. sodium
D. potassium
D. potassium
- Regarding vectorial transport across epithelial cells, transport from basolateral aspect of the cell to the apical surface is known as:
A. Absorption
B. Reabsorption
C. secretion
D. all of these
C. secretion
- Which of the following is a function of integral membrane proteins?
A. Provides negative charge to cells
B. Act as solute carriers
C. help control membrane fluidity
D. attaches one cell to the next
B. Act as solute carriers
- Which of the following factors WILL INCREASE membrane fluidity?
A. Low temperatures
B. Low amounts of cholesterol
C. increase in unsaturated fatty acids
D. increase in membrane carbohydrates
C. increase in unsaturated fatty acids
- The Na+-K+ ATPase system transports:
A. 3 potassium inside the cell and 2 sodium outside
B. 3 potassium inside and 2 sodium outside
C. 2 potassium inside and 2 sodium outside
D. 2 potassium inside and 3 sodium outside
D. 2 potassium inside and 3 sodium outside
- Which of the following transport processes is an example of primary active transport?
A Na+-glucose transport
B. Na+-K=ATPase
C. 3Na+-1Ca++ antiporter
D. Na+-H+ transport
B. Na+-K=ATPase
- There will be increased rate of gene transcription if a signaling molecule binds to which of the following?
A. Cell membrane receptors
B. Nuclear receptors
C. both
D. neither
B. Nuclear receptors
- When a signaling molecule or a hormone has “paracrine” effects, this means:
A. It acts on itself, the cell that produced the hormone
B. It acts on nearby or adjacent cells
C. It must travel long distances thru the blood to reach its target cell
D. It travels by ducts to the cell surface
B. It acts on nearby or adjacent cells
- The most common effector of G proteins is:
A. Adenylate cyclase
B. Phosphodiesterase
C. protein kinase
D. phospholipases
A. Adenylate cyclase
- Signaling molecules bind with specificity to their target cell. Which of the following is responsible for this specificity?
A. signaling molecule itself
B. transport proteins
C. receptors
D. second messengers
C. receptors
- Binding of acetylcholine to its receptor will cause activation of
A. G proteins
B. Ion channels
C. tyrosine kinase
D. enzyme linked proteins
B. Ion channels
- When a hormone/ligand binds to GPCRs (G-protein coupled receptors), one of the following occurs that signal activation of G protein:
A. Reassociation of alpha subunit to beta and gamma subunits
B. Internalization of GPCR
C. Replacement of GDP with GTP on the alpha subunit
D. Conversion of CAMP to AMP
C. replacement of GDP with GTP on the alpha subunit
- The main effect of this signaling molecule is the release of calcium from the sarcoplasmic
reticulum (SR) particularly in smooth muscles in response to some hormones:
A. CAMP
C. DAG
B. cGMP
D. Inositol triphosphate
D. Inositol triphosphate
- The breakdown of cAMP or cGMP with termination of their effects is mediated when G
protein alpha subunit binds and activates one of the following:
A. calcium
B. Phosphatases
C. phosphodiesterase
D. phosphorylase
C. phosphodiesterase
- DAG and Inositol triphosphate will be the signaling molecules generated when G protein interacts with which of the following effector molecules?
A. Adenylate cyclase
B. Guanylate cyclase
C. phospholipase A2
D. phospholipase C
D. phospholipase C
- Second messengers are activated if a hormone/neurotransmitter binds to:
A. Cell membrane receptors
B. Nuclear receptors
C. both
D. neither
A. Cell membrane receptors
- Pro-inflammatory mediators such as prostaglandins, tromboxanes and leukotrienes are produced when G protein activates which of the following effector proteins?
A. Adenylate cyclase
B. Guanylate cyclase
C. phospholipase A2
D. phospholipase C
C. phospholipase A2
- The hormone insulin activates which of the following transduction pathways?
A. Enzyme linked
B. G protein pathway
C. ion channel linked
D. regulated intramembrane proteolysis
A. Enzyme linked
- Sustained or prolonged continuous exposure to a hormone or signaling molecule will usually
cause:
A. No change in cellular response
B. Increased cellular response
C. decreased cellular response over time
D. response may increase or decrease over time
C. decreased cellular response over time
- Activation of cAMP may cause activation or inactivation of downstream intracellular proteins by phosphorylation through activation of which of the following ?
A. Protein Kinase A
B. Protein Kinase C
C. Protein Kinase G
D. Tyrosine kinase
A. Protein Kinase A
- G protein signaling is terminated when:
A. A new cAMP molecule is produced
B. A new molecule of GTP binds to the alpha subunit
C. GTP that is bound to the alpha subunit is hydrolyzed into GDP
D. ATP is converted to CAMP
C. GTP that is bound to the alpha subunit is hydrolyzed into GDP
- This is the MAJOR DETERMINANT of the resting membrane potential:
A. Potassium leak channels
B. Sodium leak channels
C. Nat-K+ATPase pump
D. voltage-gated ion channels
A. Potassium leak channels
- In chemical synapses, this is the role of calcium:
A. Responsible for neurotransmitter synthesis
B. Involved in neurotransmitter reuptake
C. Involved in neurotransmitter release from synaptic vesicles
D. Degrades unused neurotransmitters
C. Involved in neurotransmitter release from synaptic vesicles
- Increased permeability of the postsynaptic membrane to chloride or potassium ions will
result to the generation of which of the following?
A. Action potentials
B. End plate potentials
C. excitatory post synaptic potentials (EPSP)
D. inhibitory post synaptic potentials (IPSP)
D. inhibitory post synaptic potentials (IPSP)
- The most common mechanism for postsynaptic excitation is:
A. Opening of potassium channels
B. Opening of sodium channels
C. closure of chloride channels
D. closure of calcium channels
B. Opening of sodium channels
- TRUE of Inhibitory Postsynaptic Potentials;
A. Increase in negativity of postsynaptic membrane
B. Are usually hyperpolarizing
C. Decreases the probability of generating an action potential
D. All are correct
D. All are correct
- The following characterizes electrical synapses EXCEPT:
A. No pre and post synaptic elements
B. Exhibits synaptic delay
C. Transmits impulses faster
D. Cells are connected physically via gap junctions
B. Exhibits synaptic delay