Physiology: the liver 2

Question 1

what do hepatocytes secrete primary juice into

Answer 1

canaliculi which drain into biliary ductules and ducts

Question 2

give 4 contaminants of primary juice secreted by hepatocytes

Answer 2

primary bile acids, H2O + electrolytes, bilirubin and cholesterol

Question 3

excess of what component of primary juice from hepatocytes can lead to gall stones

Answer 3

cholesterol

Question 4

what is the most common pathology of the biliary tract

Answer 4

cholelithiasis(gall stones)

Question 5

describe the process of enterohepatic recycling

Answer 5

most bile salts are absorbed in terminal ileum by active transport(only 5% lost in faeces), and undergoes enterohepatic recycling

Question 6

what are the bile acid sequestrants

Answer 6

colestipol, cholestyramine and colesevalam

Question 7

describe the action of bile acid sequestrants

Answer 7

act by binding to bile acids, preventing their reabsorption