Physiology of the Urinary Tract Flashcards

1
Q

How does the kidney regulate blood pH?

A

Uses a bicarbonate buffer-system to regulate pH of blood

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2
Q

What connects the kidneys to the urinary bladder?

A

Ureters

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3
Q

What are the major functions of the kidney?

A
  • Maintain water and electrolyte homeostasis
  • Aid in maintenance of blood pH
  • Hormone production and metabolism
  • Regulation of blood pressure
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4
Q

What is the working unit of the kidney?

A

Nephron

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5
Q

Where in the kidney does blood get filtered?

A

Renal medulla

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6
Q

Where does the nephron interact with the blood vessels of the kidney?

A

Bowman’s capsule

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7
Q

Why are there so many fucking nephrons?

A
  • Increased surface area

- Redundancy

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8
Q

What mesh-network in the Bowman’s capsule separates the fluid component of blood from cells and macromolecules?

A

The glomerulus

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9
Q

What are the small holes used for transferring things in the glomerulus?

A

Fenestrae

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10
Q

When blood pressure increases, why is blood flow restricted?

A

Preserves kidney by decreasing pressure on the tiny bits of the glomerulus

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11
Q

Capsular hydrostatic pressure ______ filtrations.

A

opposes

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12
Q

Glomerular hydrostatic pressure (blood pressure) _____ filtration.

A

promotes

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13
Q

Glomerular osmotic pressure _____ filtration.

A

opposes

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14
Q

Why does high blood pressure lead to inefficient kidney function?

A

Increases in blood pressure results in release of vasoconstrictors to decrease glomerular blood pressure

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15
Q

Why is the tubule network selectively permeable at different locations for different things?

A
  • Allows for reabsorption of nutrients lost

- Allows for countercurrent multiplication

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16
Q

What does countercurrent multiplication do in the tubular network?

A

Selectively builds up concentration gradient to help move other things

17
Q

What locations of the tubular network filter out most of the sodium?

A
  • proximal tube

- loop of henle

18
Q

Why does the calcium concentration in the distal convoluted tubule not change?

A

An antiporter pumps out Ca in exchange for sodium

19
Q

Why doesn’t urea get completely filtered out?

A

Amino acid transporters in lumen of tubule mistake urea for other amino acids and reabsorbs it

20
Q

How does the kidney increase blood pressure?

A

Increases reabsorption of sodium to drive water reabsorption which will increase blood volume

21
Q

How does angiotensin increase BP?

A

Causes vasocontriction and sodium reabsorption, thus increasing blood volume