Lipids

Question 1

T or F: All naturally occurring FAs have cis double bonds.

Answer 1

True.

Question 2

Why is the delta method of FA nomenclature slightly more informative than the Omega method?

Answer 2

It specifies the locations of double bonds.

Question 3

A person eliminates fats from their diet and develops Fatty Liver Disease. What is this disease?

Answer 3

Since no fat is being consumed, the liver tries to compensate by creating lipids the body needs, covering it in fat.

Question 4

T or F: All lipids synthesized begin with acetyl-CoA

Answer 4

True.

Question 5

What two things do you need for FA synthesis?

Answer 5

• Acetyl-CoA

- Malonyl-CoA

Question 6

What is the first FA formed from the combination of acetyl-CoA and malonyl-CoA?

Answer 6

Palmitic acid

Question 7

Where are longer chain FAs made?

Answer 7

Smooth ER

Question 8

What two FAs can be used to create the other really long FAs?

Answer 8

Linoleic and linolenic acids

Question 9

What do O3 FAs make?

Answer 9

PGE2 prostaglandins which cause fevers, vasodilation and hyperalgesia (pain increaser)

Question 10

What do O6 FAs make?

Answer 10

PGE3 prostaglandins

Question 11

How does thromboxanes and prostacyclin affect clotting?

Answer 11

P - decrease

T - increase

Question 12

What do leukotrienes do to your airways?

Answer 12

Cause inflammation and smooth muscle contraction, closing the airways