Physiology: Auditory, Vestibular and Visual Systems Flashcards
role of the hair cells?
transduces vibratons to sound
transmitter in the auditory system
glutamate
three fluid-filled cavities in the cochlea
- scala tympani
- scala vestibuli
- scala media
what forms the perilymph?
scala tympani and vestibuli
what connects the scala tympani and vestibuli?
helicotrema
what does the scala tympani meet from the middle ear?
oval window
what does the scala vestibuli meet from the middle ear?
round window
what does Reissner’s membrane separate?
separates scala vestibuli and scala media
what does the basilar membrane separate?
separates scala media and scala tympani
where are the hair cells located?
they have stereocilia located on the basilar membrane with tips in the tectorial membrane
what happens to the tectorial membrane?
it vibrates causing the cilia to bend and hair cells release neurotransmitters which synapse on bipolar neurones with cell bodies in the spiral ganglion
role of the protein prestin
changes space between basilar membrane and tectorial membrane
what can furosemide inactivate?
the protein prestin and so can cause hearing loss
hair cells electrochemical current
K+ is inwards so the endolymph has a high concentration of K+ causing it to move to hair cells
what does the medial superior olivary nucleus do?
detects time interval between sound arriving at each ear
what does the lateral superior olive do?
difference in sound intensity between ears
what does the vestibular system do?
provides information about gravity, rotation and acceleration
role of the semi-circular canals?
detect head movement
what are the semi-circular canals?
3 fluid-filled (endolymph) canals at right angles to each other
structure of the semi-circular canals
contain endolymph
contain an ampulla that contains crista (hair cells)
what plane does the posterior canal share?
contralateral anterior canal
what are the otolith organs?
saccule and utricle
what do the otolith organs sense?
linear acceleration and gravity
where are hair cells located in the otolith organs?
lie in the macula and are divided by striola
crystals of calcium carbonate are called otoconia
three major vestibular reflexes
- vestibulo-ocular reflex
- vestibulo-colic reflex
- vestibular-spinal reflex
role of the vestibulo-ocular reflex?
keep eyes still in space when head moves
role of the vestibulo-colic reflex
keeps head still in space when you walk
role of the vestibular-spinal reflex
adjusts posture for rapid changes in position
dark current
constant influx of Na+, positive depolarising current causing a steady release of neurotransmiter
what happens to the dark current when exposed to light?
Na+ is reduced and efflux of K+ causes hyperpolarisation
role of centre-surround organisation/ lateral inhibition
enhances areas of difference/ contrast