Neurosurgery Flashcards
what does the sensory spinocerebellar pathway do?
sends information about unconscious proprioception to the cerebellum for posture and movement of upper and lower limbs
what does the vestibulospinal tract do?
exerts posture via extensors for legs and flexors for arms
which spinal tract increases tone?
reticulospinal tract via the pontine reflex response
which spinal tract decreases tone?
reticulospinal tract via the medullary tract
knee reflex nerves
L3/4 femoral
biceps reflex nerves
C5/6 musculocutaneous
triceps reflex nerves
C7/8 radial
ankle reflex nerves
S1/2 tibial
what type of cartilage is the annulus fibrosus made of?
fibrocartilage
three directions of prolapse for the nucleus pulposis
- paramedian (posterolateral)
- extraforaminal (far lateral)
- central/ medial herniation
paramedian prolapse
compresses tranversing nerve
herniation at L4/5 causes damage to L5 as nerve root exits below level
extraforminal (far lateral) proalpse
compresses exiting nerve
herniation at L4/5 causes L4 damage
central/ medial prolapse
lumbar stenosis or if large enough can cause cauda equina
what is a radiculopathy?
dysfunction of a nerve root causing a dermatomal sensory deficit with weakness of the muscle groups supplied by that nerve
LMN
what is a myelopathy?
UMN signs more predominant in lower limbs before progressing to upper limbs
presentation of neurogenic claudication
leg weakness
tingling
numbness
normal pulses
cause of anterior cord syndrome
cord infarction by anterior spinal artery
presentation of spinal shock
flaccid areflexic paralysis
three components of the cerebellum
- vestibulocerebellum
- spinocerebellum
- cerebrocerebellum
role of the vestibulocerebellum
balance and coordination of vestibulo-ocular reflexes
role of the spinocerebellum
maintains muscle tone and participates in posture and gait
role of the cerebrocerebellum
voluntary motor movement
presentation of thalamic infarction
hemiparesis
spontaneous pain
hemichorea
severe impairment of consciousness
appearance of glioblastoma multiforme
butterfly
appearance of oligodendroglioma
toothpaste
where do meningiomas originate from?
arachnoidal cap cells within arachnoid membrane
what are associations with meningiomas
NF2
childhood radiation
what are haemangioblastomas?
benign cystic vascular tumours in posterior fossa leading to cerebellar dysfunction and raised ICP
which are haemangioblastomas associated with?
VHL
diagnosis of AVM
catheter angiography
CTA
management of AVM
excision
radiosurgery
what is a cavernous malformation?
benign vascular lesion in sinusiodal spaces
types of aneurysms
berry/saccular
fusiform (hypertension associated)
mycotic
diagnosis of SAH
CT > LP > CTA or angiogram
grading scale for SAH
Fisher’s grading scale
grades in Fisher’s scale
grade 1= no blood seen on CT
grade 2= diffuse or vertical layers <1mm
grade 3= diffuse clot and/or vertical layer >1mm
what ischaemic penumbra?
early ischaemic stroke there is an area not functioning but has reversible damage atm
pupillary light reflex pathwya
CNII > optic tract > ipsilateral pretectal nucleus of midbrain > bilateral EWN > CNIII > ciliary ganglion > parasympathetic via short ciliary nerve > ciliary muscle and sphincter pupillae
what is neuromyelitis optica (Devic’s disease)?
bilateral severe optic neuritis and transverse myelitis in 3 or more vertebral columns (muscle weakness, increased tone and spasm)
antibody in Devic’s disease?
IgG Ab against astrocystic aquaporin 4
what causes ptosis in Horner’s?
muller muscle dysfunction
define anisocoria
unequal pupil size
what is Adie’s pupil?
loss of postganglionic parasympathetic innervation of the iris sphincter and ciliary muscle
presentation of Adie’s pupil
large pupil with blurring of near vision
absent light reflex
what does Holmes-Adie syndrome present with?
Adie’s pupil
diminished tendon reflexes of the lower limb +/- orthostatic hypotension
diagnosis of Adie’s pupil
topical pilocarpine will cause an Adie’s pupil to constrict
what is Weber’s syndrome?
form of stroke affecting the ventral midbrain
presentation of Weber’s syndrome
ipsilateral 3rd nerve palsy with contralateral hemiparesis
what is Benedikt’s syndrome?
form of stroke affecting the dorsal midbrain
presentation of Benedikts syndrome
ipsilateral 3rd nerve palsy with contralateral tremor, ataxia or chorea
what is the cogan lid twitch?
brief upshoot of lid elicited by patient looking down then up
{myasthenia gravis)
what is the ice test?
ptosis improves after applying ice for 2 minutes
clinical investigations for myasthenia gravis
antibodies
EMG
muscle biopsy
imaging for thymoma
what is the genetic inheritance of myotonic dystrophy?
AD trinucleotide repeat on chromosome 19
presentation of myotonic dystrophy
delayed muscle relaxation and wasting christmas tree cataract (early onset) ptosis hypermetropia ophthalmoplegia
what is benign essential blepharospasm?
bilateral idiopathic condition with idiopathic contraction of orbicularis oculi
management of benign essential blepharospasm
artificial tears
botox
what structures are damaged to cause decorticate posturing?
cerebrum
internal capsule
thalamus
which spinal tracts take over in decorticate posturing?
lateral CST is disrupted so rubrospinal tract causes abnormal flexion in upper limbs and reticulospinal extension of legs
what structures are damaged to cause decerebrate posturing?
level below the red nucleus of the midbrain
what spinal tracts cause decorticate posturing?
reticulospinal tract causes whole body extension
what does CSF flow through to get from the lateral to the 3rd ventircle?
foramen of Munro (intraventricular foramen)
what does CSF flow through to get to the 4th ventricle?
aqueduct of Sylvius
what does uncal herniation cause?
pupillary dilatation due to involvement of oculomotor nerve and contralateral hemiparesis
what does subfalcine hernaiton cause?
compression of anterior cerebral artery causing weakness in lower extremities
what does tonsillar herniation cause?
medullary compression
what does central herniation of the brainstem cause?
diplopia (6th nerve palsy)
brainstem dysfunction
in the spinal which part of the dura exists?
only the meningeal part
management of normal pressure hydrocephalus?
VP shunt
what are chiari malformations?
congenital or acquired conditions of the hindbrain affecting CSF circulation through the foramen magnum
chiari I malformation
caudal displacement of cerebellar tonsils, may be associated with syringomyelia
presentation of chiari I malformation
HA (coughing, suboccipital pain, neck extension)
downbeat nystagmus
central cord symptoms
ataxic gait
chiari II malformation (Arnold-Chiari)
displacement of cerebellum and medulla below foramen magnum with herniation of the 4th ventricle
what is chairi II associated with?
spina bifida
which nerve root is extensor hallucis longus specific for?
L5
what does an upgoing plantar indicate?
lesion not below L1/2 (cervical myelopathy)
presentation of cervical myelopathy
jump at night/ sitting in char
upgoing plantars
off legs
test in cervical myelopathy
Hoffman’s
management of cervical myelopathy
physio collar corticosteroid injections pain relief surgery (foot drop more urgent + progression)
types of gait
- spastic
- high stepping gait
- hemiplegic gait
- festinant gait
- shuffling gait
when is spastic gait present?
unilateral in cervical myelopathy
diplegic and scissoring in cerebral palsy
what causes high stepping gait?
foot drop (L5)
disc prolapse
front of shoe scuffed
what causes hemiplegic gait?
stroke
what muscles are involved in hemiplegic gait?
flexors strong in upper limb
extensors in lower limb
which condition has a festinant gait?
PD
which condition has a shuffling gait?
normal pressure hydrocephalus