Phosphorus Flashcards

1
Q

the majority of phosphorous in th ebody is found as

A

PO4

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2
Q

most of the P is located in the

A

bone

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3
Q

sources of P

A

dairy, meat, eggs, nuts, coffee, tea, soft drink

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4
Q

the phosphorus n all plant seeds is present in a storage form of phosphate called ____

A

phytic acid or phytate

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5
Q

why is only 50% of phytat available to humans

A

because we lack enzymes the liberate phosphorous from phytate

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6
Q

yeasts posses ____

A

phytate

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7
Q

phosphorous is absorbed in its______ form

A

inorganic

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8
Q

organically boudn phosphorous is first_____ to remove proteins it is bound to in the stomach and SI

A

hydrolyzed

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9
Q

absorption of P occurs throughout the ____

A

small intestines (duo and jeju)

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10
Q

a concentration dependent______ is the primary rout of absorptoin for phosphorous

A

facilitated diffusion

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11
Q

there is also a calcium satruable sodium dependent, carrier mediated transport system which is stimulated by______

A

calcitriol (1,25 OH)

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12
Q

phosphorous is transported in what form

A

inorganic and organic forms

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13
Q

phosphorous is mostly stored in

A

bone and muscle

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14
Q

functions of phosphorous

A
structural role
energy production
cell signalling and enzyme activity regulation
pH buffering
oxygen availability
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15
Q

phosphorous is a major structural component of ____ in the form of phosphate salt called hydroxyapatite

A

bone

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16
Q

________ are a major structural component of cell membranes

A

phospholipids

17
Q

____ and ____ are long chains of phosphate containing molecules

A

DNA and RNA (nucleic acids)

18
Q

all energy production and storage are dependent on phosphorylated compounds such as _____ and creatine phosphate

19
Q

phosphorous helps maintain normal pH by actin as one of the bodys most important intracellular _____

20
Q

the phosphorous containing molecule 2, 3 diphosphoglycerate binds to ____ in RBCs and affect oxygen delivery to tissues of the body

A

hemoglobin

21
Q

phosphorous is excreted in its _______ form primarily in the _____

A

inorganic

urine

22
Q

S&S of hypophosphatenia

A
anemia
mm weakness
bone pain and softening of bones ( rickets, osteomalacia)
peripheral neuropathy
severe = death!
23
Q

who is at risk for hypophosphatenia

A

alcoholics
diabetes recovering from an episode of diabetic ketoacidosis
people taking very high amounts of antacids

24
Q

hyperphosphatemia is only usually a problem in people with

A

end stage renal disease

25
high phosphate levels in the blood reduce the activation of ____ in the kidneys, reduce blood ____ levels, and lead to _____ release
high phosphate levels in the blood reduce the activation of [ VITAMIN D ] in the kidney reduce blood [calcium ] levels, and lead to [PTH] release
26
high serum phosphorous lead to decrease urinary ____ excretion
calcium
27
osteoporosis frequently results in
kyphosis
28
kyphosis causes
``` decreased lung capacity SOB abd pain reduced appetite premature satiety ```
29
there is an increased risk of osteoporosis in :
``` the elderly use of certain meds (glucocorticoids, thyroid hormones, antiepileptic, aromatase inhibitors) sedentary liefestyle decreased exposure to estrogen high sodium intake caffeine intake smoking chronic alcohol consumption ```
30
Naturopathic treatment of osteoporosis involves dietary supplementation of
``` vitamin d magnesium phosphorous vitamin d copper strongtioum boron manganese folic acid, b12, b6 proteins ```
31
additional naturopathic treatment of osteoporosis includes
weight bearing exercise low sodium, alcohol, caffeine, soft drinks hormonal balance enzyme/buffer balance