Pharmacy (201-250) Flashcards

1
Q

5-AR inhibitor used in the treatment of benign prostatic hyperplasia

A

Finasteride

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2
Q

Tricyclic antidepressant

A

Doxepin

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3
Q

Vitamin’s overdose toxicity cause skin changes like dryness and hyperpigmentation

A

Vitamin A

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4
Q

Lipid regulating agent of the aryloxycarbolic acid class

A

Fenofibrate

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5
Q

Surfactant laxative

A

Docusate

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6
Q

Drug with possible risk of haemolysis in some G6PD defiecient individuals

A

Aspirin

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7
Q

Drug used in neutropenia

A

Filgrastim

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8
Q

Antipsychotics is diphenylbutyl piperidine

A

Pimozide

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9
Q

Used in inflammatory bowel disease

A

Mesalazine

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10
Q

Sodium chloride 0.9% intravenous infusion contains

A

150 millimole of Na+ per liter

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11
Q

Indicated in angina pectoris

A

Glyceryl trinitrate

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12
Q

Phosphate binding agent

A

Sevelamer & Aluminum hydroxide

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13
Q

Plasma substitutes

A

Dextran, Gelatin, Hexastarch (AOTA)

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14
Q

Analogues of Spirinolactone; low dose monophasic oral contraceptive that is used to prevent pregnancy in women (antiadrogenic effect)

A

Drospirenone

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15
Q

Non acidic NSAID

A

Nabumetone

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16
Q

Histamine derivative that is used in Meniere’s disease; causes precapillary sphincters to relax; improved microcirculation in the ear

A

Betahistine

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17
Q

Indicated in non-neurological manifestations of mucopolysaccharides I

A

Laronidase

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18
Q

Anti-psychotics which is an aliphatic phenothiazines

A

Chlorpromazine

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19
Q

Indicated in nephropathic cystinosis

A

Mercaptine

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20
Q

Indicated in hyperammonaemia due to N-acetylglutamate synthase deficiency

A

Carglumic acid

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21
Q

Third generation heterocyclics used as anti-depressant

A

Mirtazapine

22
Q

Partially selective 5HT receptor agonist, accelerates intestinal transit and modulates visceral hypersensitivity used in IBS

A

Tegaserod

23
Q

SSRI used in the treatment of Premenstrual Dysphoric Disorder

A

Citalopram

24
Q

Anti-HIV protease inhibitor

A

Indinavir

25
Q

Important in metabolism as co-enzyme for variety of respiratory flavoproteins

A

Riboflavin

26
Q

Anti-anginal & antiischemic drug therapy

A

Nitrates, Beta-blockers, Calcium antagonists (AOTA)

27
Q

Suppresses the vestibular system through its action on the inhibitory effect of gamma-aminobutyric acid (GABA); used in Meniere’s

A

Lorazepam

28
Q

Antidepressant is a secondary amine tricyclic

A

Nortriptyline

29
Q

Total body potassium of a normal adult is approximately…of body weight

A

30mEq/kg

30
Q

Used to treat extrapyramidal disorders

A

Benztropine

31
Q

NSAID from propionic acid derivatives

A

Diflunisal, Etodolac, Naproxen, Nabumetone (AOTA)

32
Q

Vitamin deficiency causes Pellagra which is characterized by pigmentation and lesions of exposed skin by gastrointestinal mucosal changes

A

Niacin

33
Q

Glycolic acid ester of Indomethacin

A

Acemetacin

34
Q

Long acting glucocorticoid

A

Betamethasone

35
Q

Gold indicated in active progressive rheumatoid arthritis

A

Auranofin

36
Q

Synthetic HMG-CoA reductase inhibitor hypocholesterolemic agent

A

Fluvastatin

37
Q

Antifungal; Converted to an active metabolite which is incorporated into fungal RNA interfering with protein synthesis

A

Flucytosine

38
Q

Antimuscarinic used as mydriatic

A

Cyclopentolate HCl

39
Q

Aminoglycoside antibiotic interact with…and result in increased nephrotoxicity

A

Cephalosporins

40
Q

Fat soluble vitamin essential for calcium metabolism in animals and therefore important for normal mineralization of bone and cartilage

A

Vitamin D (water soluble vits- Vit B & Vit C

41
Q

Selective estrogen receptor modulator used in the treatment of osteoporosis

A

Raloxifene

42
Q

Acyclic nucleotide of adenosine monophosphate, which inhibits hepatitis B virus DNA polymerase; TX of chronic Hepa B

A

Adefovir dipivoxil

43
Q

Nonbenzodiazepine used in the treatment of insomnia

A

Zolpidem

44
Q

Synthetic diphenyl propylamine opiate agonist indicated for the management of opiate dependence

A

Levomethadyl acetate

45
Q

Meperidine congener that effectively inhibits excessive gastrointestinal motility

A

Diphenoxylate HCl

46
Q

Prostaglandin analogue used in the treatment of glaucoma

A

Latanoprost

47
Q

Surfactant laxative

A

Docusate

48
Q

Synthetic androgen used to suppress the hypothalamic-pituitary ovarian axis by inhibiting the release of specific gonadotropins

A

Danazol

49
Q

Biotech drug product indicated in growth failure for both pediatrics and adults

A

Somatropin

50
Q

Centrally acting inhibitor used in Alzheimer’s disease

A

Tacrine