Pharmacy (101-150) Flashcards

1
Q

Sulfonylurea; One of its metabolites has greater activity than the parent compound

A

Acetohexamide

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2
Q

Indicated in the eradication of Helicobacter pylori

A

Clarithromycin

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3
Q

Causes aplastic anemia

A

Chloramphenicol

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4
Q

Antibiotic that causes ototoxicity

A

Gentamicin

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5
Q

Oxazolidanone antibacterial drug

A

Linezolid

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6
Q

Mixture proportion of quinupristin & dalfopristin in mesilate salts

A

3 parts to 7 parts

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7
Q

Drug that inhibit hepatic metabolism of other drugs

A

Erythromycin

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8
Q

Rifinah is a combination of

A

Rifampicin & Isonizid

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9
Q

Drug that is organic acid secreted by the proximal renal tubules

A

Captopril

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10
Q

Synthetic Vitamin D3 analog for topical dermatological use

A

Calcipotriene

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11
Q

Drug indicated in leprosy

A

Clofazimine

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12
Q

Required for the synthesis of co-enzyme A (CoA) and is a component within the 4-phosphapantetheine moiety of the acyl carrier protein (ACP) domain of fatty acid synthase

A

Pantothenic acid

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13
Q

Biotech drug products indicated for the treatment of metastatic breast cancer

A

Trastuzumab

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14
Q

Irreversible inhibitor of GABA transaminase which is the main enzyme responsible for GABA degradation

A

Vigabatrin

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15
Q

Ester of Aciclovir used in the treatment of Herpes Zoster and Herpes Simplex infections

A

Valaciclovir

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16
Q

Opioid analgesics that is phenanthrene agonist

A

Morhine

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17
Q

Following drugs used to alter the menstrual cycle for the management of Pre-Menstrual syndrome (PMS)

A

Progesterone

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18
Q

Known as hypertonic albumin

A

25% albumin

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19
Q

Used in the treatment of Chronic Hepatatis C

A

Peginterferon alfa

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20
Q

Antihypertensive drug used in the treatment of alopecia

A

Minoxidil

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21
Q

Used to reduce the replication of Influenza A & B viruses by inhibiting viral neuraminidase

A

Oseltamivir

22
Q

Oral imidazotetrazine derivative that is an analog of decarbazine and used for the treatment of adults with anaplastic astrocytoma that has replaced after treatment with nitrosurea

A

Temozolamide

23
Q

Antimalarial drug

A

Chloroquine, Primaquine, Pyrimethamine, Proguanil (AOTA)

24
Q

Deficiency of this vitamin produces squamous metaplasia of the epithelial cells of the respiratory tract

A

Vitamin A

25
Q

Used in the treatment of Pneumocystis pneumonia

A

Co-trimoxazole

26
Q

Mast cell stabilizing and H1 receptor antagonist drug

A

Ketotifen

27
Q

This drug is an Ascaricide

A

Mebendazole

28
Q

Drug that causes incontinence

A

Misoprostol, Prazocin, Loop diuretics, Hypnotics (AOTA)

29
Q

1L PNSS administered…is distributed into the interstitial space and…distributed into the intravascular space

A

750ml , 250ml

30
Q

Antibiotic associated with photosensitivity

A

Doxycycline

31
Q

Tetracyclic antidepressant

A

Maprotiline

32
Q

Antispasmodic used to treat abdominal pain and discomfort associated with Irritable Bowel Syndrome (IBS)

A

Dicyclomine

33
Q

Drug which is Filaricide

A

Diethylcarbamazine

34
Q

Short acting insulin

A

Insulin Aspart

35
Q

Sulfonylureas used as oral antidiabetic drugs (EXCEPT)

A

Gliclazide, Glibenclamide, Chlorpropramide, Tolbutamide (Nateglinide)

36
Q

Inhibits conversion of cholesterol to pregnenolone and used in cancer chemotherapy

A

Aminoglutethimide

37
Q

Used to treat incontinence by inhibiting contractility and increase storage capacity

A

Prostaglandin inhibitors

38
Q

Used in the treatment of hyperthyroidism

A

Carbimazole

39
Q

Prednisolone 5mg is equivalent to…

A

Hydrocortisone 20mg

40
Q

Causes vasoconstriction of extracranial arteries & affects serotonin turnover in the brain + dpressing the firing of serotonin in the brain stem raphe

A

Ergotamine

41
Q

Mast cell stabilizer for the treatment of vernal kerato conjuctivitis, vernal conjuctivitis and vernal keratitis

A

Lodoxamide

42
Q

Distribution of 1L of 5% albumin solution

A

1000ml in the intravascular space

43
Q

Anti-estrogen

A

Clomifene citrate & Tamoxifen

44
Q

NSAID from the pyrrole acetic acid derivative

A

Sulindac

45
Q

Reduces intraoccular pressure by decreasing ciliary body aqueous humor secretion by about 50%

A

Dorzolamide

46
Q

Loop diuretic

A

Bumetanide

47
Q

Vitamin A derivative that is used in the treatment for severe, recalcitrant, nodulocystic acne vulgaris

A

Isotretinoin

48
Q

Synthetic Human Growth Hormone

A

Somatropin

49
Q

Treatment of diabetes insipidus

A

Desmopressin

50
Q

Organophosphate which is an effective pediculicide indicated in the treatment of pediculosis capitis (head lice)

A

Malathion