Pharmacology: Name of Drug With Matching Drug Action Flashcards
Furosemide
(Diuretic)
-inhibits reabsorption of sodium and chloride from the kidney and increases urinary excretion of water and electrolytes
Oxacillin
(Penicillin)
-bind to bacterial cell wall, leading to cell death
Gentamicin
(aminoglycoside)
- inhibits protein synthesis in bacteria at level 30S ribosome
- bactericidal (kills) action
Alendronate
(Bone reabsorption Inhibitor)
-inhibits reabsorption of bone by inhibiting osteoclast activities
Methotrexate
(Disease-Modifying Anti-rheumatic)
-has immunosuppressive properties and can be used to treat cancer and rheumatoid arthritis
Ciprofloxacin
(fluroquinolone)
-inhibits bacterial DNA synthesis by inhibiting DNA gyrase
Diazepam
(skeletal muscle relaxant)
-depresses the CNS and produces skeletal muscle relaxation and anticonvulsant properties
Digoxin
(anti-arrhythmic)
-increases the force of myocardial contraction
Simvastatin
(Lipid-lowering agent)
-inhibits an enzyme that is responsible for catalyzing an early step in the synthesis of cholesterol
Etanercpt
-inactivates the tumor necrosis factor that is a mediator of inflammatory response
Nitroglycerin
(Anti-anginal)
-increases coronary blood flow by dilating coronary arteries and improving collateral flow to ischemic areas
Vancomycin
for treatment of potentially life-threatening conditions, binds to cell wall resulting in cell death
Metoprolol
(anti-hypertensive)
-blocks stimulation of beta (myocardial) adrenergic receptors
Albuterol
(bronchodilator)
-inhibits muscarinic receptors, resulting in bronchodilation
Guaifenesin
(Expectorant)
-reduces viscosity of tenacious secretions by increasing respiratory tract fluid leading to mobilization and expectoration (spitting out) of mucous
Famotidine
(Histamine 2-Receptor Antagonist)
-inhibits the action of histamine at the H2- receptor site located primarily in gastric parietal cells, resulting in inhibition of gastric acid secretion
Pantoprazole
(Proton-Pump Inhibitor)
- disrupts chemical binding in stomach cells to reduce acid production
- binds to an enzyme in the presence of acidic gastric pH, preventing the final transport of hydrogen ions into the gastric lumen
Ondansetron
(Antiemetic)
- decrease nausea + vomiting
- prevent motion sickness
- blocks the effects of serotonin at 5-HT3-receptor sites (selected antagonist) located in vagal nerve terminals and the chemo-receptor trigger zone in CNS
Senna
(Stimulant Laxative)
- increases intestinal peristalsis and promotes fluid accumulation in the colon and small intestine leading to emptying the bowel
- alter water and electrolyte transport in the large intestine, resulting in accumulation of water and increases peristalsis
Loperamide
(Anti-diarrheal)
- inhibits peristalsis and prolongs transit time by a direct effect on nerves in the intestinal muscle wall
- reduces fecal volume
- increases fecal viscosity and bulk while diminishing loss of fluid and electrolytes
Insulin
(Anti-diabetic)
- lowers blood glucose
- stimulating glucose uptake in skeletal muscle and fat, inhibiting hepatic glucose production
- increases glucose transportation across muscle and fat cell membranes to reduce blood glucose levels and converts glucose to its storage form glycogen
Glipizide
(Oral Anti-diabetic)
- lower blood glucose
- stimulating the release of insulin from the pancreas and increasing sensitivity to insulin at receptor sites
- control of blood glucose in type 2 diabetes mellitus when diet therapy fails
Levothyroxine
(Hormone)
- replacement of or supplementation to endogenous thyroid hormones
- increasing metabolic rate of body tissues
- stimulate protein synthesis
- promote cell growth and differentiation
- aid in development of the brain and CNS
