Pharmacology Chapter 19 & 20 Flashcards
Endorphins
…are ENDOGENOUS ANALGESICS produced within the body as a reaction to severe pain or intense exercise. i.e. runner’s high
Subjective
It can be experienced or perceived only by the individual subject.
Placebo Effect
Relief from pain as the result of suggestion w/o the administration of analgesic.
Analgesics
…are given to relieve pain. They can be classified as opioids, non-opioids, and adjuvant.
Sedatives
…are given to calm, sooth, or produce sedation.
Hypnotics
…are given to produce sleep.
Endogenous
Produced or originating within a cell or organism.
Opioids
…are controlled substances in the US and include both the natural opium alkaloids, like morphine and codeine, and the synthetics, such as meperidine (Demerol) and propoxyphene (Darvon).
Tolerance
A larger dose of opioid is needed to achieve the same level of analgesia
Dependence
A physical adaptation of the body to the opioid and withdrawal after abrupt drug discontinuation.
Co-algesic
Non-opioid analgesic drugs that are combined with opioids for more effective analgesic action in relief of acute or chronic pain.
Antipyretic
Medication to reduce fever.
Tinnitus
Ringing or roaring in the ears.
Adjuvant
A drug added to a prescription to hasten or enhance the action of a principle ingredient.
Paradoxical
Opposite effect from that expected.
Psychotropic
Refers to any substance that acts on the mind.
SNRI - Selective Norepinephrine Reuptake Inhibitor -
Antidepressants that block the reabsorption of serotonin, thus helping to restore the brain’s chemical balance.
Antidepressant
Medication used to treat patients w/various types of depression - mood elevators.
Neurotransmittors
Substances that travel across the synaptic gap of 2 nerve cells, carrying a message from one to the other.
SSRI -Selective Serotonin Reuptake Inhibitors
Antidepressants that blocks the reabsorption of of serotonin, thus helping to restore the brain’s chemistry.
Tricyclics
Antidepressants that elevate the mood, have a mild sedative effect and increase appetite.
Heterocyclic
Second generation cyclic antidepressant with very different adverse affect profiles.
Bipolar Disorder
Manic-Depressive mental disorder in which mood fluctuates from one extreme to the other.
Anxiolytics
Anti anxiety medications are sometimes referred to as anxiolytics or minor tranquilizers
Ataxia
Defective muscular coordination, especially w/voluntary muscular movements, i.e. walking
Antipsychotic
Major tranquilizers used to relieve symptoms of psychosis or severe neuroses.
Extrapyramidal Side Effects -EPS
Disorder of the brain characterized by tremors, parkinsonlike symptoms etc.
Tardive Dyskinesia - TD
Slow, rhythmical, stereotypical, involuntary movements such as tics.
Atypical Antipsychotics
A newer class of anti psychotics with less potential for adverse effects such as TD, and EPS.
Addiction
Physical and/or psychological dependence on a substance, alcohol or drugs, with use of increasing amounts (tolerance)
And withdrawal reactions
Chemical Dependency
A condition in which alcohol or drugs have taken control of an individual’s life and affect normal functioning.