Pharmacology Flashcards

1
Q

Define action potential

A

the electrical/chemical way info is transmitted from cell to cell

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2
Q

at rest the neuron contains which elements

A

outside is excess sodium, inside is excess potassium

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3
Q

What creates action potential

A

when a stimulant is sufficient enough to cause the sodium and potassium to switch places

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4
Q

Where are neurotransmitters released to

A

the synaptic cleft

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5
Q

Name two things that can happen when a neurotransmitter is released

A

it can bind to adjacent dendrites or reuptake occurs

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6
Q

what happens when dendrites capture neurotransmitters

A

the flow of information is continued

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7
Q

what happens in the reuptake process

A

the neurotransmitters such as serotonin do not make it to the other neuron, instead they are sucked back into the terminal buttons

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8
Q

which neurotransmitter is low in depression

A

serotonin

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9
Q

What do SSRI’s do

A

inhibits reuptake of serotonin so that more serotonin can make it to the adjacent neuron

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10
Q

Define agonist

A

anything that enhances the effect of the neurotransmitter

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11
Q

Define antagonist

A

anything that inhibits the neurotransmitter effect

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12
Q

Define excitatory neurotransmitter

A

increases likelihood of action potential

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13
Q

Name three excitatory neurotransmitters

A

acetylcholine, epinephrine, glutamate

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14
Q

Define inhibitory neurotransmitters

A

decreases likelihood of action potential

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15
Q

Name two inhibitory neurotransmitters

A

GABA, endorphins

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16
Q

What are the most common neurotransmitters in the brain

A

acetylcholine and glutamate

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17
Q

Which neurotransmitter aids in voluntary movement, memory, and cognition

A

acetylcholine

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18
Q

What structure of the brain is acetylcholine active in

A

the hippocampus

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19
Q

Dementia/Alzheimers is a result of a deficiency of which neurotransmitter

A

acetylcholine

20
Q

Name two catecholamines

A

dopamine and norepinephrine

21
Q

Which catecholamine is involved in movement, thinking, and emotion

22
Q

Which neurotransmitter is linked to the reward system of the brain

23
Q

Are traditional antipsychotics antagonists or agonists

A

antagonists- block dopamine receptors

24
Q

What is the process called if a neurotransmitter is blocked

25
Second generation antipsychotics are agonists of which neurotransmitters
dopamine and serotonin, they block the dopamine receptors
26
Parkinsons results from degeneration of the neurons that transmit dopamine
true
27
What is L-Dopa treatment
dopamine agonist, enhances dopamine in the brain
28
Norepinephrine (or noradrenaline) is involved with what
mood, sleep, and pain
29
depression is a result of
deficiencies of norepinephrine (noradrenaline)
30
mania is a result of
excess norepinephrine (noradrenaline)
31
Serotonin is involved in
many things; mood, sleep, appetite, aggression, pain, perception, sexual activity
32
dysregulation of which neurotransmitter is associated with suicidality and impulsivity
serotonin
33
Too little serotonin usually results in what
mood disorder
34
name three amino acids
GABA, glycine, glutamate
35
Name two major inhibitory neurotransmitters (calming effect)
GABA and glycine
36
Too little GABA results in which disorders
anxiety disorders and seizure disorders
37
What type of medication is a GABA agonist
Benzodiazepines
38
In addition to dopamine, which neurotransmitter is implicated in schizophrenia, OCD, autism, and depression
glutamate
39
What are enkephalins and endorphins
bodies of opioids
40
Are opioids natural pain killers
yes
41
define lipid soluble
capability of substance to dissolve in lipids (fats and oils)
42
generic drugs have the exact same pharmacological effects as brand name drugs T/F
true
43
which schedule of drug has the highest potential for abuse and have no medical qualities
schedule 1
44
schedule 2 drugs do not have potential for abuse and dependence T/F
false, they have high potential for abuse and dependence and have SOME medicinal qualities
45
What schedule drug is meth considered
schedule 2
46
How many schedules of drugs are there
5
47
Drugs are scheduled based on what
their potential for abuse