Antidepressant Medications Flashcards
Classes of antidepressants include
Tricyclic, SSRI, Atypical, SNRI, NRI, MAO
Side effects of tricyclics
anticholinergic, adrenergic, antihistamine, misc
Tricyclics do not have many side effects T/F
false. they are considered a dirty drug that interact with many receptors and can cause serious side effects
Selective Serotonin Reuptake Inhibitors (SSRI) are safer than tricyclics and have fewer side effects T/F
True
Side effects of SSRI’s and atypical antidepressants include
Anxiety, Sedation, Insomnia, Nausea, and sexual dysfunction
elavil 75-150
cyclic antidepressant
anafranil 100-250
cyclic antidepressant
norpramin
cyclic antidepressant
tofranil 75-200
cyclic antidepressant
pamelor 25-100
cyclic antidepressant
oleptro
cyclic antidepressant
Serotonin and Norephinephrine Reuptake Inhibitors (SNRI) are more effective than SSRI’s for severe depression
True
Effexor 75-375
SNRI
Pristiq 50
SNRI
Cymbalta 20-80
SNRI
Fetzima 40-120
SNRI
Remeron 15-45
SNRI
Norepinephrine Reuptake Inhibitors (NRI) are used mainly for depression
False. They are mainly used for ADHD.
NRIs positive and negative side effects include
Improved energy and cognition. Cause anxiety, loss of apetite, sedation
Wellbutrin 200-450
atypical antidepressant
Serzone
atypical antidepressant
BuSpar 15-60
atypical antidepressant
Viibryd 10-40
atypical antidepressant
Trintellix 5-20
atypical antidepressant
Monoamine Oxidase Inhibitors (MAOI) are the first treatment for depression
False, they are mainly used when other antidepressants have failed for the treatment of major depression and panic disorder
MAOIs are dangerous if eating foods high in tyramine
true
The two most common MAOIs are
Nardil and Parnate
Which MAOs type B are used for depression in Parkinsons
Deprenyl and Ensam
Are stimulants used to treat depression
Yes, Dexedrine and Ritalin
How long does it take for an antidepressant to be effective and how long should they be continued
2-4 weeks, 6 months
Antidepressants work by blocking the reuptake of which neurotransmitters
norephinephrine, serotonin, and dopamine
Can antidepressants increase suicidality
Yes
Which OTC options can help treat depression
St. John’s wort, SAM-e, Omega-3 fatty acids
common uses are
major depression, SAD, panic disorder, OCD, enuresis, ADHD, chronic pain syndromes, PTSD
a common side effect is sexual dysfunction
true
The first choice in antidepressants is currently
SSRI new generation
Which antidepressants are not used much anymore
TCAs (tricyclic antidepressants), MAOI (monoamine oxidase inhibitors)
reasons to use antidepressants in the elderly
pseudodementia, pharmacokinetics, hypotension, peripheral
what is serotonin syndrome
drug interaction with MAOIs, increase serotonin levels, mental status changes, lack of coordination, muscle twitching, tremors, sweating, fever, needs medical care
