PHARMA/MED Flashcards
Causes hyperexcitation?
Fipronil
Mode of action of fipronil.
Blocking GABA-gated chloride channels and glutamate-gated chloride
This plant is used in olden times as dewormer.
a. niyog niyogan (Combretum indicum)
b. sambong (Blumea balsamifera)
c. *
d. *
A. niyog niyogan (Combretum indicum)
Useful component of guava leaves used as antioxidant .
Guava has a high content of protocatechuic acid, quercetin, ferulic acid, ascorbic acid, quercetin, gallic acid and caffeic acid which are important antioxidants.
Sagot ni doc Weng is CATECHIN
Toxic component of mushroom.
AMANITOXINS as well as gyromitrins, and orellanine
Toxic to pet birds.
AVOCADO
Toxic in swine atleast it was cooked.
CASSAVA (cyanogenic glucosides)
What type of vaccine is used in orf virus (Contagious ecthyma)?
a. Killed
b. Live
c. Attenuated
d. Modified
B. Live (Merck)
Added to vaccines to add more immune response
a. Adjuvant
b. Dilution
c. *
d. *
A. Adjuvant
Failure of vaccine in farm is due to?
a. Putting in refrigerator
b. Dilution proportion
c. *
d. *
b. Dilution proportion
- Handling
Influenza vaccination in horses for travel.
a. 4 months
b. 6 months
c. 1 year
d. *
b. 6 months
Antidote for organophosphate poisoning
2-PAM
Mode of action of 2 PAM.
Cholinesterase activity
Induce parturition in mare?
Oxytocyn
Withdrawal period of chlortetracycline in poultry (but the question is situational type)?
0 DAYS
Treatment for plasmodium?
Quinilones
Safest and easiest Injection site in parrots.
Right jugular vein and basilic vein.
-medial metatarsal vein may be more accessible in some large avian species
Why avoid holding snake in the head?
a. Avoid vertebral injury
b. Avoid getting bitten
c. *
b. Avoid getting bitten
How to lift small size dog?
h. One hand in the thorax
i. One hand in abdomen one hand in neck region
j. *
h. One hand in the thorax
Site of blood connection when the dog is in sitting position.
a. Saphenous
b. Cephalic
c. Jugular
d. *
b. Cephalic
Mycobacterium is resistant to what disinfectant?
a. Phenol
b. Alcohol
c. Quats
a. Phenol
Not used as antiseptic in hands that assisted in the removal of fetus in dogs positive of
BRUCELLOSIS?
Alcohol
Leucocytozoonisis Treatment:
Treatment usually is not effective. Preventive medication using pyrimethamine (1 ppm) and sulfadimethoxine (10 ppm) combined in the feed controls L caulleryi. Clopidol (0.0125%–0.025%) controls L smithi. Measures to control invertebrate vectors are helpful. Humoral immunity resulting from vaccination will protect against L caulleryi infection. Treatments with quinacrine hydrochloride or trimethoprim/sulfamethoxazole solution have been used in raptors; parasitemia is reduced, but the infection is not cleared.
Toxin in sudan grass?
NITRATE
Blue algal poisoning Treatment?
After removal from the contaminated water supply, affected animals should be placed in a protected area out of direct sunlight. Ample quantities of water and good quality feed should be made available. Because the toxins have a steep dose-response curve, surviving animals have a good chance for recovery. Although therapies for cyanobacterial poisonings have not been investigated in detail, activated charcoal slurry is likely to be of benefit. In laboratory studies, an ion-exchange resin such as cholestyramine has proved useful to absorb the toxins from the GI tract, and certain bile acid transport blockers such as cyclosporin A, rifampin, and silymarin injected before dosing of microcystin have effectively prevented hepatotoxicity. No therapeutic antagonist has been found effective against anatoxin-a, cylindrospermopsin, or the saxitoxins, but atropine and activated charcoal reduce the muscarinic effects of the anticholinesterase anatoxin-a(s).
Tilmicosin fumarate computation.
- 2% Tilmicosin fumarate in 10 kg feeds
QUINIDINE
Quinidine is a medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
LIDOCAINE
Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. It is also used to treat ventricular tachycardia
How priceless is your unfailing love, O Lord! Both high and low among men find refuge in the shadow of Your wings.
- Psalm 36:7
YOU CAN DO IT, VEIN!!!
in anaphylactic shock?
EPINEPHRINE
GENTAMICIN SULFATE
for optic solution
Both antitrematodal and. Anticestodal?
PRAZIQUANTEL.
For whipworm?
Febantel
Sprayed to remove aggression in group of boars?
Estrogen, progesterone, andosterone, etc
Carbamate MOA?
acetyl cholinesterase inhibition in the nervous system.
Carbamate acts on:
a. muscarinic
b. Nicotinic
c. Both
d. Central nervous reflex
c. Both
Tx for fungal infection of lungs in bird ?
a. Nystatin
b. Amphotericin B
b. Amphotericin B
Mannhemia hemolytica
Florphenicol
Antitussive for progressive cough
Guaiafenesin
Treatment for leukocytozoon.
a. Marcolides
b. Sulfonamides
c. Combine (check merck)
b. Sulfonamides
What vitamin will be deficient (in)????
Folic acid
Computation. How much tiamulin will be added in 10kg feeds for 10 pigs weighing 20kg each.
20 mg/kg
Question about puffer fish.
What toxin?
Tetrodotoxin
What organ of the fish contains the toxin?
a. Liver
b. Muscle
a. LIVER
When ingested, what organ will be mostly affected ?
a. Heart
b. Stomach
c. Diaphragm
c. Diaphragm
Use of toxin in pharma?
Pain reliever
Dog swims in pond with blue thing floating. It causes diarrhea, seizure. What is the cause?
a. Algae
b. Campylobacter
c. OP
E. coli?
a. Algae
What can be associated with mushroom poisoning?
Acetylcholine (same with atropine in action or effect
Same question #48. What is the receptor ?
Muscarinic
Injectable anesthetics for caged birds?
Ketamine
Inhalant anesthetics for avian?
I
Isoflurane (ref: check stateboard ancillary topics)
Given to horse before race to avoid epistaxis?
a. Furosemide
b. Vitamin B12
c. Vitamin K
a. Furosemide
This drug has been used extensively for the treatment of bleeding in horses since the mid-1970s. Lasix works by reducing the stress on horses organs by lowering the amount of fluid retained in the body just before the horse races.
Toxic substance present at Cassava
Linamarin
Substance present in guava
Tannic acid
Most common antihistamine in the market used by man?
a. Dipenhydramine
b. Loratadine
c. Dextrametorphan
d. Ephedrine
a. Dipenhydramine
Tx of choice for chlamydia
Doxycycline
Drugs that are un synergism
Macrolides and TMPS? Aminoglycosides and cephalosphorin? Other choices are cidal + static thus not compatible
Which drug cannot be mixed with (forgot the drug)?
Ans: penicillin
Half-life of oxytocin?
a. 1-2 mins
b. 3-4 mins
c. 30 sec
d. 5 -10 mins
Oxytocin has a plasma half-life of about 1 to 6 minutes which is decreased in late pregnancy and during lactation. Following intravenous administration of oxytocin, uterine response occurs almost immediately and subsides within 1 hour.
Ceftiofur computation
Dose given in IU around 3 questions
How many ml is 2% drug in 10 kg sack?
200 ml
How many to be given in 10 pigs?
2000 ml
How many is needed in 10 days?
20, 000 ml
Why are birds sensitive to fumes of sodium hypochlorite?
Skin sensitivity (stateboard question, skin will be burn)
Not an H1 blocker?
a. Cetirizine
b. Loratidine
c. Dypenhydramine
d. meclizine
c. Dypenhydramine
Not a cause of leptospirosis?
Flying birds
Immunization of lepto in bulls?
Every 12 months
Cannot be used with lidocaine?
a. LRS
b. Epinephrine
c. Ephedrine
d. PCN
b. Epinephrine
cases of gangrene (ears, noes, toes/ digits)
Same with lidocaine use for tx of ventricular tachycardia?
Quinidine
Used to slowdown the heartbeat.
Verapamil
Given to dogs ingested gasoline/ diesel?
a. H202
c. Vegetable oil
c. Petroleum
a. H202
Can kill sperm when added?
a. Erythromycin
b. Gentamycin
c. Rifampin
d. Metronidazole
a. Erythromycin
and trimethoprim-sulfamethoxazole, or a quinolone.
NSAIDS
Cyclooxygenase inhibitor
Common arsenical growth promotant for poultry?
Roxarsone?
Pig reacted to vaccination. What to administer?
Choices are Combination of drugs and its amount (5 ml epineph and pencilillin 20, 000 IU?)
Effect of glucocorticoid in ophthalmic problem?
Perforation?
Milk of magnesia question
Magnesium Hydroxide (laxative)
Milk of amnesia
Propofol
Heartworm treatment
Milbemycin
Canine distemper signs and treatment
Myoclonus; supportive care and efforts to prevent secondary infections; control vomiting, diarrhea and neurologic symptoms; and combat dehydration through administration of fluids.
Eyedrops for dogs
Gentamycin
Proper ways to prevent eye problems in dogs?
Surgery? Clean and trim the hair on the sides of the eye?
Use to kill tapes in ruminant?
Fenbendazole
Cadiac glycosides
Digoxin
To induce parturition
Oxytocin
To relax brochiolar muscle
Epinephrine
Influence of BBB in patient with mengintis
Penicillin
Termination of pregnancy
PGF2a
Organophosphate poisoning antidote
Atropine or 2PAM
Drug of Choice for Erysipelas
Penicillin
Which anti emetic drug is not safe for pregnant bitch?
a. Meclicine – teratogenic
Toxic component of ipil ipil
Mimosine
Toxic component of Cassava
Linamarin
Why 2 PAM is given slow IV?
May cause respiratory arrest
Effect of Aspirin
thinning of blood
Inhibits prostaglandin/antiplatelet
Aspirin, Asaphen, Entrophen, Novasen) Clopidogrel (Plavix) Prasugrel (Effient) Ticagrelor (Brilinta)
Hormone secreted in posterior pituitary gland
Oxytocin
Effect of dexamethasone when given in late term pregnancy?
Premature parturition
- Transport requiring energy
a. Active
b. Passive
c. Facilitated
c. Facilitated
Dog and cat fight, when eyes are punctured what to use?
a. Ointment with anti inflam
b. Eyedrops with anti inflam
b. Eyedrops with anti inflam
Drunk monkey
Coma
When methanol is oxidize it becomes
Formic acid - same as the substance secreted by ants
Anti-emetic in primates
Cannabinoid Agonists
ermination of pregnancy
PGF2a
Best drug to use to induce parturition in horse
Oxytocin
Decreased/reduce absorption in the presence of food
Amoxicillin
Psittacosis DOC
Doxycycline
Effect of epinephrine in bronchiolar smooth muscles
Relax
Fenbendazole Tx in sheep what ds?
roundworm infection
Cardiac drugs except?
a. pimobendan
b. enalapril
c. amlodipine
d. diltiazam
a. pimobendan - manage congestive heart failure (CHF)
b. enalapril - ACE (angiotensin-converting enzyme) inhibitor. it relaxes and widens your blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body
c. amlodipine - Amlodipine is a calcium channel blocker medication used to treat high blood pressure and coronary artery disease.
d. diltiazam - Diltiazem is used to prevent chest pain (angina)
Cause of laminitis in horse
overeating (obesity), working on a hard surface (commonly referred to as road founder), running high fevers, exposure to black walnut shavings, and stress. Ponies are extremely susceptible to laminitis, especially when fed rich, lush forage
Drug to alleviate laminitis in horse
Phenylbutazone 2.2–4.4 mg/kg IV or PO every 12 hours
Flunixin meglumine 0.5 –1.1 mg/kg IV or PO every 12 hours
Firocoxib 0.1 mg/kg PO every 24 hours
Drug to be given in overdose of calcium blocking drugs?
Calcium gluconate
Enalapril
(ACE inhibitor)
Drug banned for fattener pigs
clenbuterol
Fentanyl
Fentanyl is an opiate narcotic medication that is used by veterinarians to treat animal patients suffering from moderate to severe pain. It also can be used as a sedative or tranquilizer in some animal patients.
powerful opioid used as a pain medication and together with other medications for anesthesia. It is also used as a recreational drug, sometimes mixed with heroin, methamphetamine, or cocaine. It has a rapid onset and its effects generally last under two hours.
Antibiotic that cause colic in horses
Lincosamide
Cardiac glycosides
Cardiac glycosides are a class of organic compounds that increase the output force of the heart and increase its rate of contractions by acting on the cellular sodium-potassium ATPase pump.
Penicillin is not used in rabbit lagomorphs because.
a. Allergy
b. Kills gram + bacteria
c. Kills gram – bacteria
d. ?
Use antibiotics such as penicillin with caution in rabbits. Oral penicillin is associated with gastrointestinal disease in this species.
Which drug is used to kill tapeworm in ruminants
a. Fenbendazole
b. Praziquantel
c. Ivermectin
b. Praziquantel - but not approved for small ruminants
Property of a drug that allows it to cross BBB.
Lipid solubility
Withdrawal period of tulathromycin
cattle - 22 days
pigs - 13 days
sheep - 16 days
Withdrawal period of tylosin
Discontinue use in cattle 21 days before slaughter. Discontinue use in swine 14 days before slaughter. Do not use in lactating dairy cattle. A withdrawal period has not been established for this product in pre-ruminating calves
Withdrawal period of tilmicosin
The recommended withdrawal time is 10 days. Tilmicosin is rapidly absorbed and slowly eliminated after oral administration.
Vine with anticholinergic?
Belladona (used for atropine)
Farmer asking veterinarian
• When is the pig safe to eat after vaccination
• What to give to pigs to promote growth
• Withdrawal period of ranitidine
Ranitidine
Furosemide excretes
(sodium, potassium, and chloride)
What type of diuretic is spironolactone?
Potassium-sparing diuretic
Longest withdrawal period
IM ivermectin (other choices are topical)
Amphotericin B causes bone dss when administered with what drugs?
Chloramphenicol or Sulfa
Antitussive.
Dextromethorphan
Amikacin(aminoglycosides) is not used with
not be used with neuromuscular blocking agents, as they can increase muscle weakness and paralysis.
- succinylcholine, rocuronium, vecuronium, atracurium, cisatracurium, mivacurium
CNS stimulant at low dose but toxic at high doses.
Caffeine, strychnine
Fermenting baking dough produces what alcohol?
Ethanol
Dog ingests rubbing alcohol, what clinical signs will be observed?
Disorientation and loss of body control.
Your dog may appear weak.
He may begin to vomit violently.
Diarrhea will occur as your dog’s body tries to rid itself of the poison.
He may salivate excessively sometimes foaming at the mouth.
Excitement gives way to lethargy and depression.
Dog licked sodium hydroxide on the floor of the clinic, what clinical signs will be observed?
Vomiting Diarrhea Gastrointestinal lesions Lack of appetite Swollen abdomen Burns or lesions in the mouth Excessive watering of the mouth Disorientation Muscle weakness Seizures Collapse Eye irritations Skin irritation Hair loss
Antihistamines and side effects (3qts)
• What are the side effects of antihistamine administration?
Drowsiness. Dry mouth, dry eyes. Blurred or double vision. Dizziness and headache. Low blood pressure. Mucous thickening in the airways. Rapid heart rate. Difficulty urinating and constipation.
Neonatal cattle with diarrhea treatment
a. Na + glucose
b. NaCl
c. Na + fructose
d. Lactose
b. NaCl
Anesthetic contraindicated for Boxers
a. Xylazine
b. Methoxyflurane
c. Ketamine
a. Xylazine?
NOT a sign of Betel nut toxicity?
a. Nystagmus
b. Vomiting
c. Diarrhea
d. Altered heart beat
d. Altered heart beat
NOT used with furosemide due to physical characteristic?
a. Cimetidine
b. 5% dextrose NaCL
c. Amikacin
d. Another aminoglycoside
c. Amikacin (Kasi synthetic analog ng kanamycin?)
Used with Polymixin B.
a. Furosemide
b. Mannitol
a. Furosemide
Alcohol situation:
a. Butanol
b. Ethanol
c. Methanol
d. Isopropyl
????
Intermediate of methanol in liver metabolism?
Formaldehyde
Blindness in monkey is a result of?
a. Ketosis
b. Acetonemia
a. Ketosis
Synergist with Kanamycin
cephalosporins
Organophosphate for horse?
a. Dichlorvos
b. Coumaphos
c. OP
a. Dichlorvos
Antibiotic that does not need to attach to ribosome?
a. Pleuromutilin
b. Sulfonamide
c. Tetracycline
d. Chloramphenicol
b. Sulfonamide
Tiamulin situation: A 1000 birds currently weighing 900 grams each is ready for market after 1 week. Sudden Mycoplasma infection to the chickens. (Dose: 20 mg/kg)
How many grams of Tiamulin to treat the flock?
a. 140 g
b. 72 g
c. 120 g
d. 18 g
d. 18 g
How many mL of water the birds will drink in 32oC?
a. 250
b. 150
c. 200
d. 270/100
agcompute ka!! :P
How many mL Tiamulin to add to water if 1 mL Tiamulin has 250 mg activity?
a. 55
b. 72
c. 42
b. 72
Diphenhydramine situation: Most common adverse reaction to diphenhydramine?
a. Diarrhea
b. Hyperexcitability
c. Lethargy
d. Vomit
c. Lethargy
Least common adverse reaction to diphenhydramine?
a. Diarrhea
b. Hyperexcitability
c. Lethargy
d. Vomit
b. Hyperexcitability
Charcoal & Gentian violet burned in a pot, what will be formed?
a. Aldehyde
b. Benzene
c. Oxalic acid
a. Aldehyde
Treatment for urea toxicity?
5% acetic acid into rumen
What to inject in a delayed fetal expulsion with tinge blood mucus?
a. Palpate, oxytocin 15
b. Palpate, oxytocin 20, dexamethasone
c. Palpate, oxycotin 15, MgSO4
c. Palpate, oxycotin 15, MgSO4
Furosemide dosage and frequency.
5 mg/kg (2-4mg/kg)
Dosage of thiamine/B1 in poultry.
4 mg/kg (Merck)
Drug combination that lead to periportal hepatitis.
Niclosamide and pyrantel
MOA of levamisole.
Agonistic activity in nicotinic Ach receptor
Fipronil contraindicated to:
A.Rabbits
B.Kitten
C. Dog
D. Cat
A.Rabbits
Fipronil has a narrow margin of safety in rabbits. Its administration is contraindicated because of the potential for life-threatening signs and the availability of safer alternative spot-on products for external parasite control.
Withdrawal period of chlortetracycline in avian?
0 day (Merck)
Vaccine administration for Newcastle disease in a flock?
A.Aerosol spray
B. Intranasal
C. Wing vein
D. Intraocular
A. Aerosol spray - healthy chickens 14 days of age or older
Revaccination is recommended at four weeks and 16 weeks of age.
Vincristine is tx.for?
Transmissible venereal tumor (TVT)
Vinblastine is tx.for?
Mast cell tumor
Antibiotics which target 30s ribosomal subunit?
SAT (sulfonamide, aminoglycoside, tetracycline)
Antibiotics which target 50s ribosomal subunit?
CLM (chlorampenicol, lincosamides, macrolide)
DOC for avian campylobacteriosis?
Erythromycin
Dewormer recommended for pregnant cattle?
A.Benzimidazole
B.Levamisole
C.Ivermectin
B.Levamisole (Merck)
Universal antidote
Activated charcoal
Loop diuretic?
Spironolactone
pwede ring furosemide
Myasthenia gravis supportive care.
Neostigmine - works by slowing the breakdown of acetylcholine when it is released from nerve endings.
MOA of quinolone.
Inhibit of DNA gyrase
MOA of disinfectant (Alcohol)
lipid solubility (damage bacterial membrane)
Disinfectant are used only for disinfecting?
Inanimate objects
Open-type pyometra treatment.
A.PGF2 alpha
B.oxytocin
A.PGF2 alpha
Sertoli cell tumor treatment.
Increase secretion of estrogen
Treatment of Rhodococcus equi infection?
Rifampin and erythromycin
Antibiotic contraindicated for neonates?
Quinolones - due to concerns of age-related drug toxicities stemming from observed cartilage toxicity in weight-bearing joints of immature animals during preclinical animal experiments.
Classification of laxative.
Bulk (senna)
Triclabendazole.
Liver fluke
Withdrawal period of amoxicillin?
30 days
Withdrawal period of oxytetracycline (LA) for cattle?
28 days
Dosage of albendazole for liverfluke in ruminants?
20 mg/kg
Triclabendazole dosage for liverfluke in ruminants?
10 mg/kg
Treatment of tumor in pancreas?
dTTP -Deoxythymidine triphosphate
Delay healing of corneal ulceration.
Steroids (dexamethasone
Adrenal cortical tumors.
Mitotane (o,p’DDD)
Drug of choice for coccidiosis in poultry?
Amprolium (0.0125-0.025% in feed)
withdrawal period of Amprolium in Poultry:
0 day
The drug most likely to cause gastrointestinal ulceration or erosion in a dog?
a. erythromycin
b. dexamethasone
c. ibuprofen
d. trimethoprim-sulfadiazine
c. ibuprofen
Which of the following is (1) not bacteriostatic, (1) bactericidal?
Note: Carbapenems are penicillin
Drug that do not belong?
Note: Random drugs, unsure of parameter to differentiate.
Used to control vomiting in Parvovirus infection in dog?
metoclopramide
When to use colloids?
a. increase extracvascular volume
b. increase intravascular volume
b. increase intravascular volume
Anticonvulsant for post-distemper epilepsy?
phenobarbital
Anticonvulsant for dog that sniffed –?
Diazepam?
After 6 hours, cat still have seizures after OP intoxication?
a. prolonged AchE inhibition
b. drug ineffective
?
Epinehprine in anaphylactoid shock to?
increase heart rate and blood pressure
For treatment of TVT?
vincristine
Computation. Note: B1-thiamine, B2-riboflavin
Drug A (2%) for 8kg, 3mg/kg every 4 hours.
How many to administer on first day?
8𝑘𝑔 𝑥 3𝑚𝑔 | 𝑘𝑔 𝑥 100𝑚𝑙 | 2𝑔 𝑥 1𝑔 | 1 000𝑚𝑔= 1.2𝑚𝑙/𝑑𝑜𝑠𝑒
1.2𝑚𝑙 | 4ℎ𝑟 𝑥 24ℎ𝑟 | 𝑑𝑎𝑦= 𝟕.𝟐𝒎𝒍/𝑑𝑎𝑦
Drug B (10ppm) 10mg/pig/day for 100 pigs. How many of the drug per day?
100𝑝𝑖𝑔𝑠 𝑥 10𝑚𝑔 | 𝑝𝑖𝑔 𝑥 1 000 000𝑚𝑔 | 10𝑚𝑔
=100 000000𝑚𝑔 | 𝑑𝑎𝑦
=𝟏𝟎𝟎𝒌𝒈/𝑑𝑎𝑦
Test for rate of excretion of drug?
K+ excretion
Not in dehydration with vomiting and diarrhea?
a. LRS
b. 0.9% saline
c. 5% dextrose
d. 5% amino acid
???
Pre-anesthetic that causes vomiting in dog?
a. xylazine
b. ketamine
c. acepromazine
d. atropine
a. xylazine
When both atropine and acetylcholine injected?
a. only sympathetic response
b. only parasympathetic response
c. only muscarinic response
Note: No only nicotinic response
Main site of drug excretion?
kidney/urine
Action of Doxapram?
enhance breathing
OP antidote?
atropine
Dosage of atropine as antidote?
0.2-2mg/kg?
Yellow taint on humerus, adverse effect of?
tetracycline
Major adverse effect of penicillins?
hypersensitivity
Ibuprofen is contraindicated in?
cats
Excretion of spironolactone?
a. chelation
b. hydrolysis
??
Effect of enrofloxacin?
articular cartilage erosion
To enhance excretion of barbiturates
alkalinize urine
Not to be used in food-producing animal?
chloramphenicol
Which drug is cns stimulant in low dose but toxic in high dose? –
a. cocaine,
b. theobromine,
c. amitriptyline,
d. strychnine
a. cocaine, pwede ring strychnin
Which is not antagonist of the effect of atropine?
Pilocarpine
Priority banned drug of FDA when importing horses from EU?
Choices are all banned drugs here in Philippines
Give folic acid to prevent anemia in dogs. Dosaging of folic acid?
2.5 mg bid
Furosemide computation
…
Sulfa not being used in layer –
high tendency of drug residue in egg
Drug used for CBPP when released after quarantine – TCN or Tylosin
high tendency of drug residue in egg
Shipping fever, metaphylaxis stage –
TCN (Metaphylaxis is a newer term used to describe the treatment of an entire group of calves with an antibiotic upon arrival at your farm. Currently, several antibiotics are labeled for metaphylaxis)
Site of action of furosemide
Furosemide is a potent loop diuretic that works to increase the excretion of Na+ and water by the kidneys by inhibiting their reabsorption from the proximal and distal tubules, as well as the loop of Henle. It works directly acts on the cells of the nephron and indirectly modifies the content of the renal filtrate.
Withdrawal period of anthrax vaccine –
30, 60 days?
Withdrawal period: Do not slaughter animals for human consumption within 21 days after vaccination.
- Merck
Do not belong?
a. PCN,
b. TCN,
c. Linco,
d. Chloram
????
Enroflox, when is safe to use in dogs?
Enrofloxacin should not be used in pets that are allergic to it, in dehydrated pets, in small and medium breed dogs under 8 months of age, or in large breed dogs that have not finished their rapid-growth phase. It should not be used in cats with kidney disease.
Drug with broad therapeutic index
warfarin. lithium. digoxin. phenytoin. gentamicin. amphotericin. 5-fluoro-urocil. zidovudine.
Fecalysis revealed hookworm, dipylidium, toxocara? Which antihelmintic is to be used?
???
OP that causes cerebral agenesis when sprayed in pregnant sow?
birukem
Longest withdrawal period?
a. Topical
b. injectable ivermectin
injectable ivermectin
Drug that is not used in non-productive cough?
…
Treatment for shock after administration of combined bacterin –
a. Dexa
b. epinephrine
…
a potassium sparing effect=
spironolactone
The flock was treated with tilmicosin onapril 5. when will it be safe to be slaughtered to avoid antibiotic residue ?
april 20- 10 days withdrawal period
Similar question in Tilmicosin withdrawal period in 2 except that the species is swine?
10 days withdrawal period
There are 200 cattle in the herd. Available drug is oxytetracycline 100 mg/ bottle. How many bottles do you need to prevent anaplasmosis throughout the tick season? Hardest question. Assume body weight of cattle (250 kg), must know the preventive dose for oxytet( 20 mg/kg?), tick season ( 6 months ?)
…..
Time when TAT is given to foals if the mare is vaccinated before foaling?
3 months?
Withdrawal period of levamizole-
7 days
Norfloxacin in layer is administered through?
Drinking water
organophosphate for horses=
dichlorvos
op antidote=
atropine
Fluid to give when there is severe dehydration and diarrhea =
lactated ringers
The dog’s skin was burned by caustic soda. Which of the following will you use to treat the wound?
Virgin coconut oil
atropine is for what receptor=
muscarinic
atropine has similar effects with=
mushroom poisoning
MOA of Ivermectin
( GABA Inhibitor)
MOA Sulfonamides
( DNA synthesis inhibitor)
MOA of vincristine which can make it effective for TVT-
mitotic spindle function inhibitor
Not given in horses=
minocycline, monensin
Causes discoloration of teeth in young animals=
TCN
always accompany atropine in OP poisoning=
2 pam
avoid giving antitussives when there is
non-productive cough
to pass the BBB, a molecule should be=
lipophilic
treatment for anaplasma=
tetracycline
Fipronil is an
acaricide
Fipronil distribution is through
diffusion
a loop diuretics=
furosemide
Antibiotic used in cases of meningitis is under the family of? –
a. Cell wall inhibitors?
b. Macrolides?
c. Aminoglycosides?
c. Aminoglycosides - inhibit protein synthesis
Drug used to treat diabetes insipidus –
vasopressin
Irritant to the stomach of dog –
ibuprofen
MOA of sulfonamides –
competitive antagonism? (walang PABA sa choices hehe)
Difference between enrofloxacin and ciprofloxacin –
3x potent ang enro or cipro or vice versa, more stable in acid?
MOA of ivermectin –
inhibition of GABA
Which of the following is an example of systemic route of drug administration?
– intrapleural
Which of the following is an example of local route of drug administration?
– intraarticular
Drug of choice for chlamydiasis
– oxytetracycline
Antibiotic that does not cross the BBB
– trimetophrim?
Antibiotic that does not cross the BBB
– sulfa?
Property of an antibiotic making it to pass the BBB –
non-protein bound???? or lipophilic? or non-ionized???
Withdrawal period of TMPS
– 10 days
Withdrawal period of Amoxicillin –
a. 10 days?
b. 15 days?
c. 20 days?
d. 30 days?
7 days sa google
Withdrawal period of Oxytetracycline in poultry–
5 days?
The declared withdrawal periods of Oxytetracycline were 7days and safe level of that antibiotics were 120µg/kg respectively. The results indicated that the declared withdrawal periods and safe level of Oxytetracycline are almost nearest position which is shown in (google)
Antidote for malathion poisoning –
atropine
Acepromazine is an example of pre-anesthetic. It can be used together with –
xylazine
Chlorpromazine is contraindicated in horses because? –
a. it can cause ataxia?
b. Horse cannot metabolize it?
c. Anaphylaxis?
(wala sa choices yung penile paralysis
Can cause drowsiness –
sedative
Anticoccidial that is antagonistic with tiamulin –
monensin
Nutrient derived from tryptophan –
niacin?
Vitamin needed for the metabolism of amino acid –
biotin
Vitamin E is easily decomposed by –
a. alkali?
b. Acid?
c. Heat?
d. Light?
/..
Vitamin A is easily decomposed by –
a. alkali?
b. Acid?
c. Heat?
d. Light?
….
The senior vet prescribed methazolamide. It is indicated for?-
glaucoma
What would be the best anthelmentic to use against worm larvae of dogs?
a. ivermectin?
b. Fenbendazole?
c. Pyrantel?
d. Piperazine?
…
Which of the following has the highest therapeutic index? – penicillin? Gentamicin? Sulfa?
…
Most easily controlled anesthetic?
a. Halothane?
b. Methoxyflurane?
a. Halothane
Treatment of DIC –
heparin sulfate
Glucagon is indicated during? –
decrease blood glucose
Withdrawal period of oxytetracline in salmonids?
21 days
21 days din sa catfish
30 days sa lobsters
What will be the effect if both atropine and acetylcholine where injected in the animal?-
a. Both sympathetic and parasympathetic will occur?
b. Ach will act of muscarinic receptors?
…