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USMLE > Pharm5 - Pharm5 > Flashcards

Pharm5 - Pharm5 Flashcards

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USMLE® Step 1 flashcards
1
Q

class thioridizine

A

typical antipsychotic

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2
Q

class haloperidol

A

typical antipsychotic

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3
Q

class fluphenazine

A

typical antipsychotic

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4
Q

class chlorpromazine

A

typical antipsychotic

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5
Q

class clozapine

A

atypical antipsych

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6
Q

Class olazapine

A

atypical antipsych

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7
Q

class risperidone

A

atypical antipsych

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8
Q

class fluoxetine

A

ssri

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9
Q

class paroxetine

A

ssri

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10
Q

class sertraline

A

ssri

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11
Q

class citalpram

A

ssri

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12
Q

class imipramine

A

tca

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13
Q

class amitriptyline

A

tca

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14
Q

class desipramine

A

tca

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15
Q

class nortiptyline

A

tca

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16
Q

class clomipramine

A

tca

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17
Q

class doxepin

A

tca

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18
Q

class buprorpion

A

heterocyclic

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19
Q

class venlafaxine

A

heterocyclic

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20
Q

class mirtazapine

A

heterocyclic

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21
Q

class maprotiline

A

heterocyclic

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22
Q

class trazadone

A

heterocyclic

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23
Q

class phenylzine

A

maoi

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24
Q

class tranylcypromine

A

maoi

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25
Q

toxicity associated with ssri

A

gi distress anorgasmi a seratonin syndrome if given with maoi

26
Q

sx of seratonin syndrome

A

hyperthermia muscle rigidity cv collapse

27
Q

how long does it take for antidepressants to work

A

2-3 wks

28
Q

side effects of tca

A

sedation alpha-blocking effects atropine like effects (tachy, urinary retention)

29
Q

which generation of tca s have more anticholinergic effects? give an example of the drug

A

3rd amitryptyline

30
Q

which tca is least sedating

A

desipramine

31
Q

toxicity assocaited with tcas

A

tri-c’s convulsions coma cardiotoxicity respiratory depression hyperpyrexia confusion and hallucination in elderly (d/t anticholinergic effects)

32
Q

which class of drugs is used to treat alcohol w/d

A

benzos

33
Q

which class of drugs is used to treat anorexia/bulemia

A

ssri

34
Q

which drugs are used to treat anxiety

A

buspirone benzos/barbiturates (take a shorter time to work) MAOI

35
Q

which drugs are ssris?

A

paroxetine fluoxetine sertriline citalopram

36
Q

which class of drugs is used to treat atypical depression

A

maoi

37
Q

which class of drugs is used ot treat bipolar d/o

A

lithium carbamazepine valproic acid

38
Q

which drugs are used to treat depression

A

ssri tca

39
Q

which drugs are used to treat depression with insomnia

A

trazadone mirtazapine

40
Q

which drugs are used totreat OCD

A

climipramine ssri olanzepine

41
Q

which drugs are used to treat panic d/o

A

tca buspirone

42
Q

toxicity associated with maois

A

hypertensive crisis associated with ingesting wine/cheese (tyramine)

43
Q

drug interactions assicated with maois

A

b-blockers ssri (–> both cause seratonin syndrome)

44
Q

MOA venlafaxine

A

inhibits 5HT, NorE, and DA reuptake

45
Q

toxicity of venlafaxine

A

stimulant effects sedation nausea constipation increased BP

46
Q

MOA mirtazapine

A

alpha-2 antagonist (increased release of NorE and 5HT) and potent 5HT2, 3 receptor antagonist

47
Q

toxicity of mirtazapine

A

sedation increased appetite weight gain dry mouth

48
Q

moa maprotiline

A

blocks NorE reuptake

49
Q

toxicity of maprotiline

A

sedation orthostatic hypotension

50
Q

moa trazadone

A

inhibits 5HT reuptake

51
Q

toxicity of trazadone

A

sedation nausea priapism postural hypotension

52
Q

MOA dantroline

A

blocks the release of ca from SR of skeletal muscles

53
Q

uses of dantroline

A

nms malignant hyperthermia

54
Q

wha tcan cause malignant hyperthermia

A

inhalation of anesthetics and succinylcholine

55
Q

what are the different types of NM blocking agents

A

depolarizing and nondepolarizing

56
Q

ex of a depolarizing NM blocking agent

A

succinylcholine

57
Q

ex of nondepolarizing NM blockign agent

A

anything with a ‘cur’ in it

58
Q

uses of NM blockign agents

A

to paralyze muscles in surgery or mechanical ventilation

59
Q

what are the 2 phases of depolarizing NM blockade?

A

1: continuous depolarization 2: gradual repolarization with resistance

60
Q

how do you reverse the depolarizing blockade at phase 1? phase 2?

A

administer cholinesterase inhibitors (eg: neostigmine or physostimine) during PHASE

61
Q

how do you reverse the non-depolarizing blockade?

A

cholinesterase inhibitors (eg: neostigmine, edrophonium)

USMLE (16 decks)

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