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SMB 4 > Pharm- Opiods > Flashcards

Pharm- Opiods Flashcards

1
Q

Morphine- Indications

A

Severe pain, gold standard opiate.

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2
Q

Morphine- MOA

A

Blocks substance P, alters perception of pain, centrally acting

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3
Q

Morphine- AE

A

Constipation, respiratory depression

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4
Q

Hydromorphone- Indication

A

Severe pain! Better for patients with renal impairment

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5
Q

Hydromorphone-MOA

A

Inhibits substance P, binds to opioid receptors

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6
Q

Hydromorphone-AE

A

constipation, resp. depression, addiction

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7
Q

Tylenol with Codeine- Indications

A

Moderate to severe pain, antitussive

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8
Q

Tylenol with Codeine- MOA

A

Acetaminophen- inhibits prostaglandin synthesis, pain impulse
Codeine- Binds to opiate receptors, inhibits ascending pain pathway, suppresses cough

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9
Q

Tylenol with Codeine- AE

A

Resp. depression, dizziness, caution in renal & hepatic impairment

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10
Q

Hydrocodone- Indications

A

Moderate to severe pain

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11
Q

Hydrocodone- MOA

A

Converted to morphine in liver- blocks opioid receptors.

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12
Q

Hydrocodone- AE

A

CNS depression, constipation

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13
Q

Oxycodone- Indications

A

Moderate to severe pain

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14
Q

Oxycodone- MOA

A

Semisynthetic derivative of morphine

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15
Q

Oxycodone- AE

A

Resp depression, constipation, increased intracranial pressure

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16
Q

Meperidine- Indications

A

Acute pain, short term use

17
Q

Meperidine- MOA

A

Binds to Mu receptors, different than morphine. Synthetic

18
Q

Meperidine- AE

A

Anxiety, tremors, muscle twitch, lower seizure threshold

19
Q

Methadone- Indications

A

Chronic pain management, withdrawal from opioids due to long life

20
Q

Methadone- MOA

A

Strong agonis- binds to mu and NMDA receptor increasing duration of effects.

21
Q

Methadone- AE

A

Euphoria, hypotension, liver & renal failure

22
Q

Tramadol- Indications

A

Mild & neuropathic pain

23
Q

Tramadol- MOA

A

Weak agonist, inhibits uptake of neurotransmitters, CNS inhibition

24
Q

Tramadol- AE

A

Seizures, anxiety, N/V, sedation

SMB 4 (15 decks)

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