Pharm- NSAIDs

Question 1

Naproxin- Indications

Answer 1

Less CV activity than other NSAIDs

Question 2

Naproxin- MOA

Answer 2

COX inhibitor- reduces prostaglandin & thromboxane

Question 3

Naproxin- AE

Answer 3

GI bleeding, ulcer, dyspepsia

Question 4

Naproxin- Dosing

Answer 4

250-500 mg q 12h for antiinflammation. Don’t exceed 1250 mg/day

Question 5

Aspirin- Indication

Answer 5

Original NSAID, more commonly used for CV now

Question 6

Aspirin- MOA

Answer 6

Anti platelet (irreversible binding to platelets), COX inhibitor, antipyretic.

Question 7

Aspirin- AE

Answer 7

Reyes syndrome, GI bleeds, rashes, toxicity

Question 8

Celebrex- Indications

Answer 8

Patients at high risk for GI bleeds, NSAID intolerance,

Question 9

Celebrex- MOA

Answer 9

Selective COX 2 inhibitor

Question 10

Celebrex- AE

Answer 10

CV & GI side effects, anemia

Question 11

Ibuprofen- Indications

Answer 11

Pain & inflammation

Question 12

Ibuprofen- MOA

Answer 12

COX inhibitor

Question 13

Ibuprofen- AE

Answer 13

GI & CV

Question 14

Indomethacin- Indications

Answer 14

Bursitis, OA, tendonitis

Question 15

Indomethacin- MOA

Answer 15

NSAID- COX inhibitor

Question 16

Indomethacin- AE

Answer 16

Lower risk of CV events than others, higher GI

Question 17

Meloxicam- Indications

Answer 17

OA, RA

Question 18

Meloxicam- MOA

Answer 18

NSAID- Cox inhibitor, increased COX 2 inhibition

Question 19

Ketorolac- Indications

Answer 19

Pain- severe to moderate

Question 20

Ketorolac- MOA

Answer 20

Increased COX 2 inhibitor

Question 21

Ketorolac- AE

Answer 21

GI