Pharm of the liver Flashcards

1
Q

Only ____ drug can bind to receptors and have a pharm effect

Drug is not ______ when protein boudn

high doses of aceto

A

unbound

eliminated

deplete glutathione, allowing toxic intermediates to accumulate

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2
Q

Isoniazid neuritis tx

Rifampin SE

Ribavirin is used alongside

Structure

SE

A

VB6

Orange urine

Pegylated interferon

Guanosine analog

anemia, heart problems

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3
Q

Pegylated interferon

SE

Sofosbuvir SE

Paritaprevir

A

inhibits viral replication

Flu like sx

fatigue/HA

Sleep loss, rash, itching

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