Cirrhosis addt'l Flashcards
1
Q
Hepatocyte damage results in
Chromatin condensation
Fragmentation
As hepatocytes die
A
accumulation of fat (Steatosis) and bilirubin (cholestasis)
Pyknosis
Karyorrhexis
Parenchymal repair occurs, result in nodules
2
Q
As hepatocytes are lost
scarring typically involves
A
fibrous septa encircle, forming a scar
portal tracts and central veins
3
Q
Prehepatic
Intraheptaic
Posthepatic
Causes of portal HTN
A
Portal vein thrombosis
Portal vein narrowing
Splenomegaly
Cirrhosis
Hepatic vein outflow obstruction
RHF
4
Q
MCC of cirrhosis
Common sx in female
Male
A
Chronic viral hep (HepB/C)
F- amennorhea
M- hypogonad, infertility, ipotence
Caput medusae
5
Q
MC hematologic abnormality
Dx tests
Biopsy findings
A
Thrombocytopenia
LFTs, serum Na, PT/INR
Upper endoscopy
Hepatocyte loss, nodules formed, scarring
