Liver Patho Flashcards
1
Q
Cells in the liver
Fxn of kupffer cells
Hepatic stellate cells
A
hepatocytes, bile duct and sinusoidal epithelial cells, kupffer cells, lymphocytes, stem cells
Remove toxins/tumor cells/virus/bacteria
Store VA
2
Q
Acetominphen OD
Acetaminophen death typical pt
A
ETOH or meds inc CYP2E1 activity, minimal breakdown
Chronic ETOH user
3
Q
Impaired hepatic metabolism of estrogen sx
Other sx of cirrhosis
A
Palmar erythema, spider angioma, gyncecomastia, amenorrhea
DC, clubbing
Portal HTN
4
Q
Portal HTN sx
A
Esophageal varices
Ascites
Splenomegaly
Hepatic encephalopathy
5
Q
Fatty liver dz assoc with
A
hypercholesterolemia/triglyceridemia, obesity
6
Q
Effects of alcohol
A
Fatty change Steatohepatits to cirrhosis Enhance HepB/C Pancreatitis Enhanced drug toxicity
7
Q
Diet pills/supplements
A
can cause hepatic problems