Liver Patho Flashcards

1
Q

Cells in the liver

Fxn of kupffer cells

Hepatic stellate cells

A

hepatocytes, bile duct and sinusoidal epithelial cells, kupffer cells, lymphocytes, stem cells

Remove toxins/tumor cells/virus/bacteria

Store VA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Acetominphen OD

Acetaminophen death typical pt

A

ETOH or meds inc CYP2E1 activity, minimal breakdown

Chronic ETOH user

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Impaired hepatic metabolism of estrogen sx

Other sx of cirrhosis

A

Palmar erythema, spider angioma, gyncecomastia, amenorrhea

DC, clubbing
Portal HTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Portal HTN sx

A

Esophageal varices
Ascites
Splenomegaly
Hepatic encephalopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Fatty liver dz assoc with

A

hypercholesterolemia/triglyceridemia, obesity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Effects of alcohol

A
Fatty change
Steatohepatits to cirrhosis
Enhance HepB/C
Pancreatitis
Enhanced drug toxicity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Diet pills/supplements

A

can cause hepatic problems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly