Cholangiocarcinoma Flashcards

1
Q

Cholangiosarcoma

Majority located in

A

Malignancy of biliary tree, in bile ducts

perihilar/CBD

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2
Q

Patho

Influenced by

Rf

A

Stepwise accumulation of genetic abnormalities

inflammtion/cacinogen exposure

PSC, congenital biliary anomalies, liver fluke infestation, cholelithiasis/cholecystitis

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3
Q

Eval of pt with obstructive jaundice

Then

Tumor markers

A

US- biliary tract dilation proximal to tumor

MRCP/CT- tumor with bile duct obstruction

may be present- CA 19-9 >
1000 (usually seen in PSC)

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4
Q

Management

A

Surcical resection for localized

Alongside chemo/rad

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