GI Overview Flashcards
Digestive tract
Aka
Accessory organs
Mouth to Anus
Alimentary canal
Teeth/tongue/salivary glands/ liver/gall bladder/pancreas
Function of the GI tract
Must have
Requires
supply CV system with usable nutrients
Digestion (breakdown of large non diffusible molecules into absorbable units)
Enzymes to aid/speed chemical rxns
Molecules move via
Transport occurs by
simple diffusion carrier mechanisms (facil diffusion, active transport)
Motility
Mostly_____, except for
Secretion
muscular contraction of GI tract for propulsion and mixing
Involuntary, chewing/swallowing/defecation
Digestive juices secreted into lumen of GI tract and hormones
Digestion
Absorption
Breakdown of stuff via chemical rxns, governed by temp/enzymes
Transport of digestion products into blood (via SI)
Endocrince secretions
Gastrin, secretin, CCK, GIP, motilin
Layered organization
Blood and lymph vasculature
Absorptive cells lining the lumen, with neural and muscular components below
Abundant to transport absorbed nutrients
Mucosa has
ME contractions
Myenteric plexus
microvilli on membane, villi on folds to inc SA
Move food through tract, mixing food
Fibers and ganglia of both SNS and PNS
Enteric NS
Allows for
site where PNS fibers synapse with PG neurons that innervate SM
Many S PG nerves synapse on neurons
Local regulation of the GI tract
ENS coordinates
Modified bt
digestion, secretion, motility to optimize absorption
Info from CNS and local chemical/mechanical sensors
Kallikrein
Bradykinin
causes breakdown of kininogen to bradykinin
causes local vasodilation to inc blood flow to the actively secreting gland