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SMB 3 > Pharm- Metabolic bone disorders > Flashcards

Pharm- Metabolic bone disorders Flashcards

1
Q

Bisphosphates- Indications

A

Osteoporosis, paget disease & hypercalcemia

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2
Q

Bisphosphates- MOA

A

Decreases osteoclastic bone resorbtion- decreases osteoclast formatio,, increases apoptosis, inhibits cholesterol pathway

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3
Q

Bisphosphates- AE

A

diarrhea, abd pain, musculoskeletal apin, esophagitis

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4
Q

Selective estrogen receptor modulators- Indications

A

Post menopausal bone loss, prevents osteoporosis

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5
Q

Selective estrogen receptor modulators-MOA

A

Binds to estrogen receptors, preventing bone resorbtion

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6
Q

Selective estrogen receptor modulators-AE

A

DVT, hot flashes, PE, stroke

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7
Q

Calcitonin- Indications

A

Postmenopausal osteoporosis, relieves pain associate with fracture, Paget disease

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8
Q

Calcitonin- MOA

A

Inhibits osteoclast activity

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9
Q

Calcitonin- AE

A

Hypersensativity, N/V, flushing, rash

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SMB 3 (11 decks)

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