Myopathic syndromes

Question 1

Polymyalgia rheumatic- Eti

Answer 1

Women over 50. Often in conjunction with giant cell arthritis

Question 2

Polymyalgia rheumatic-Sx

Answer 2

Stiffness and aching of shoulders, neck & hips

Question 3

Polymyalgia rheumatic-Dx

Answer 3

Elevated ESR & symptoms

Question 4

Polymyalgia rheumatic-Tx

Answer 4

Prednisone & NSAIDs

Question 5

Polymyositis- Eti

Answer 5

Unknown origin autoimmune disease, common in 5th-6th decade, women, white

Question 6

Polymyositis- Sx

Answer 6

Gradual & progressive muscle weakness of proximal muscle groups, extremities and neck. Pain & tenderness, difficulty swallowing

Question 7

Polymyositis– Dx

Answer 7

Autoantibody serology & Sereum muscle enzymes- creatinine kinase aldolase. Muscle biopsy

Question 8

Polymyositis- Tx

Answer 8

High dose corticosteroids- prednisone

Question 9

Dermatomyositis- Eti

Answer 9

Common in over 50 yrs, male, white

Question 10

Dermatomyositis- Sx

Answer 10

Dusky red malar rash on face, neck, shoulder, chest & back- shawl sign. Periorbital & periungual edema with inflammatory arthritis

Question 11

Dermatomyositis- Dx

Answer 11

Serum muscle enzymes- creatanine kinase, autoantibodies, muscle biopsy

Question 12

Dermatomyositis- Tx

Answer 12

Limit sun exposure, high dose prednisone