Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

SMB 3 > Pharm-Antirheumatic > Flashcards

Pharm-Antirheumatic Flashcards

1
Q

Methotrexate- Indications

A

Ra & psoriatic arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Methotrexate- MOA

A

folate agonist- inhibits lymphocyte proliferation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Methotrexate- AE

A

stomach ulcers, nausea, cirrhosis of liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hydroxychloroquine- Indications

A

Mild RA, combined with methotrexate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Hydroxychloroquine- MOA

A

inhibits phospholipase A2, and platelet aggregation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Hydroxychloroquine- AE

A

ocular toxicity, retinal damage, CNS disturbances, GI upset, skin discoloration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Sulfasalazine- Indications

A

Early, mild RA in combination with hydroxychloroquine & methotrexate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Sulfasalazine- MOA

A

Unknown, COX & prostaglandin inhibition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Sulfasalazine- AE

A

Leukopenia, anorexia, HA/N/V, hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Azathioprine- Indications

A

RA, lupus, psoriatic arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Azathioprine- MOA

A

T-lymphocyte inhibition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Azathioprine- AE

A

mutagenic in pregnancy, leukopenia, thrombocytopnea, anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Penicillamine- Indications

A

Slows progression of bone destruction and RA- in conjunction with NSAIDs/ glucocorticoids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Penicillamine- MOA

A

Unknown, prevents cycstine calculi, removes excess heavy metals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Penicillamine- AE

A

Severe! dermatologic nephritis, aplastic anemia,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Ethanercept- Indications

A

Moderate to sever RA, psoriatic arthritis, ankylosing sponylitis

17
Q

Ethanercept- MOA

A

TNF inhibitor

18
Q

Ethanercept- AE

A

Infection at injection site, sepsis

19
Q

Infliximab- Indications

A

In conjunction with methotrexate- RA, psoriatic arthritis, ankylosing spondylitis

20
Q

Infliximab- MOA

A

Antibody- TNF alpha inhibitor

21
Q

Infliximab- AE

A

Infusion site reaction, chills, pruritis, urticaria, opportunistic infections

SMB 3 (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions