pharm exam 3 Flashcards
disease that affects person’s brain behavior and leads to inability to control legal and illegal drugs
substance use disorder
what are the 4 qualifiers of D5M5?
mental disorders
1. deviance
2. dysfunction
3. distress
4.danger
taking meds that aren’t prescribed, wrong dose, someone else’s Rx, or just to feel the affects
misuse
physical vs phycological withdraw from addiction
physical: increased HR & n/v
phycological: emotional or angry or mood swings
patients reduced reaction to a drug following its repeated use
tolerance
unpleasant sensory & emotional experience caused by stimuli
pain
what is pain stimulation based on?
opioid receptors in the nervous system & stimulation from chemical mediators
minimum point at which something causes your pain
threshold
maximum amount of pain that you can handle
tolerance
class of drugs designed to relieve pain without causing loss of consciousness
analgesia
abnormal sensation
dysesthesia
pain from a normally non-painful stimuli
allodynia
describe the drug schedules
1 = most potential for abuse
4 = least potential for abuse
what are the medicine steps of pain management? (mild to severe)
1- mild pain
(non opioid meds)
2- moderate pain
(weak opioid med, non opioid meds, adjuvant analgesia)
3- severe pain
(strong opioid med, non opioid meds, adjuvant analgesia)
what meds are non opioids?
NSAIDS & Acetaminophen(tylenol)
what meds are NSAIDS?
1st generation:
ASA(aspirin)
mortin(ibuprofen)
advil
toradol
naproxen
2nd generation:
celebrex
what are NSAIDS used for?
mild to moderate pain:
decrease pain, inflammation, and platelet aggregation (by inhibiting COX enzymes)
NSAID side effects
GI upset, GI bleeding, ulcers, tinnitus
*second generation (Celebrex) doesn’t affect GI tract and platelet function
NSAID nursing considerations
dont give to active bleeding pts
dont give to kidney disease pts (monitor BUN & creatinine increases)
what is acetaminophen(tylenol) used for?
mild to moderate pain
h/a
fever (antipyretic)
acetaminophen(tylenol) side effects
generally no SE but possible rash, n/v, and anorexia
acetaminophen(tylenol) nursing considerations
can cause liver damage (check AST & ALT)(jaundice)
can cause cyanosis (blue) if take a toxic dose
morphine
meperide (demerol)
hydromorphine (dilaudad)
codeine
Lortab
oxycontin
Percocet
methadone
opioids
opioid side effects
n/v
constipation
hypotension (& orthostatic)
decrease RR
urine retention
itching
what are opioids used for?
to block painful stimuli in nervous system, suppress respirations, & cough
what are opioids made from?
opium poppy plant
opioid nursing considerations
dont give to pts with low BP (hypotension)
monitor BP & RR
what is the opioid reversal agent?
naloxone (narcan)
what are the 4 signs of inflammation?
heat, redness, swelling, pain
what are the 2 inflammatory mediators?
prostaglandins & COX enzyme
what are the 4 anti-inflammatory meds?
NSAIDS
Steroids
DMARDS (disease modifying anti-rheumatic drugs)
Antigout drugs
what do steroids do?
suppress inflammation & adrenal function
what are steroid meds?
“-sone”
hydrocortisone (cortef)
methylprednisolone (Solu-medrol)
prednisone
dexamethasone (decadron)
steroid side effects
- increase BG, BP, HR, appetite, risk for infection
- Na & water retention
- decrease K
- osteoporosis
- mood changes
- irritability
- insomnia
- moon face
- HTN
steroid teaching
short term
must be tapered to quit
decrease salt intake
take w meals
watch for hypokalemia
steroid nursing considerations
- dont give a live vaccine to someone on steroids
- monitor BG, BP, WBCs
- observe for hyperglycemia
- dont crush prednisone
- to decrease or prevent GI upset: take w food; may need to take with H2-receptor antagonist [cimetidine or ranitidine]
used to alleviate pain and cause loss of consciousness by depression of CNS through decreasing firing of neurons and other mechanisms
anesthetics
what 4 anesthetic states come from general anesthesia?
- unconscious - not aware of self or environment
- sedation - dont move
- analgesia - dont feel pain
- amnesia - dont remember
general anesthesia side effects
cardiac and respiratory depression
hypotension
n/v
dysrhythmias
hyperthermia
general anesthesia nursing considerations
monitor ABC’s, BP, HR
nitrous oxide
midazolam (versed)
fentanyl (innovar, sublimaze)
propofol (diprivan)
general anesthetics
anesthetics that are IV & inhaled
general anesthesia
anesthetics that are topical route
local anesthesia
what do local anesthetics do?
only block pain in a specific part
DONT affect consciousness
lidocain (Xylocaine)
local anesthetic
bupivacaine (Marcaine)
regional anesthetic