Phaeochromocytoma Flashcards

1
Q

define phaeochromoctyoma?

A

catecholamine-producing tumours that usually arise from chromaffin cells of the adrenal medulla

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2
Q

what are the tumours called if they are not on the adrenal glands?

A

paragangliomas

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3
Q

what is a big risk factor for phaeochromocytoma ?

A

• Familial cases are seen in patients with:
o MEN2a
o von Hippel-Lindau syndrome
o Neurofibromatosis type 1

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4
Q

what are the classical features of phaeochromocytoma ?

A
  • Headache
  • Sweating
  • Palpitations
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5
Q

what are the signs of phaeochromocytoma ?

A
  • Hypertension
  • Postural hypotension
  • Pallor
  • Tachycardia
  • Fever
  • Weight loss
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6
Q

what is the first line investigation for phaeochromocytoma ?

A

• 24 hr urine collection of metanephrines

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7
Q

what investigation should be carried out after urinary collection?

A

CT chest abdomen and pelvis

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