Hypogonadism - females

Question 1

define hypogonadism in females?

Answer 1

characterised by impairment of ovarian function

Question 2

examples of primary hypogonadism?

Answer 2

o Gonadal dysgenesis e.g. Turner’s syndrome)

o Gonadal damage

Question 3

examples of secondary hypogonadism?

Answer 3

o Functional
o Pituitary/Hypothalamic Tumours and Infiltrative Lesions
o Hyperprolactinaemia
o Congenital GnRH deficiency

Question 4

symptoms of oestrogen deficiency?

Answer 4

o	Night sweats  
o	Hot flushing  
o	Vaginal dryness  
o	Dyspareunia 
o	Decreased libido 
o	Infertility

Question 5

signs pre - puberty of hypogonadism?

Answer 5

o	Delayed puberty 
o	Eunuchoid (long legs, arm span greater than height)

Question 6

signs post - puberty of hypogonadism?

Answer 6

o Regression of secondary sexual characteristics

Question 7

signs of hypothalamic/ pit disease?

Answer 7

visual field defects

Question 8

key sign of kallmanns?

Answer 8

anosmia

Question 9

key features of turners syndrome?

Answer 9

o Short statue
o Widely spaced nipples
o webbed neck
o Ejection systolic murmur due to bicuspid aortic valve

Question 10

what will LH and FSH and oestrogren be for a primary disorder?

Answer 10

• high LH / FSH

- low oestrogen

Question 11

what will LH and FSH and oestrogren be for kallmans?

Answer 11

• low LH and FSH

- low oestrogen