hypogonadism - males Flashcards
define hypogonadism?
a syndrome of decreased testosterone production, sperm production or both
examples of primary hypogonadism in males?
o Gonadal dysgenesis
e.g. Klinefelter’s syndrome
o Gonadal damage
examples of secondary hypogonadism in males?
o Pituitary/Hypothalamic lesions
o Kallmann’s syndrome
o Hyperprolactinaemia
o Prader-Willi syndrome
what is the most common cause of hypogonadism in males?
Klinefelter’s Syndrome
presenting symptoms of hypogonadism?
- Delayed puberty
- Decreased libido
- Impotence
- Infertility
signs of hypogonadism - prepubertal?
o Signs of delayed puberty • High pitched voice • Decreased pubic/axillary/facial hair • Small or undescended testicles • Small penis o Gynaecomastia o Eunuchoid proportions
signs of hypogonadism - post-pubertal?
o Decreased pubic hair
o Soft and small eyes
o Gynaecomastia
o Fine perioral wrinkles
how will primary hypogonadism present? T and LH and FSH?
- low testosterone
- high LH and FSH
how will secondary hypogonadism present? T and LH and FSH?
o Low testosterone
o Inappropriately normal/low LH and FSH
