PERIPHERAL NEUROPATHY Flashcards

1
Q

symptoms of large fibre motor loss?

A

-weakness
-unsteadiness
-wasting

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2
Q

symptoms of large fibre sensory damage?

A

-numbness
-paraesthesia
-unsteadiness

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3
Q

symptoms of small fibre nerve damage

A

-pain
-dysthesia

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4
Q

symptoms of autonomic nerve damage

A

-dizziness (postural hypotension)
-impotence
-nausea and vomiting (gastroperesis)
-absence of sinus arrythmia

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5
Q

what is the power, sensation and reflexes like for large fibre motor nerve damage?

A

power- reduced
sensation- normal
reflexes- absent

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6
Q

what is the power, sensation and reflexes like for large fibre sensory nerve damage?

A

power- normal
sensation- vibration and JPS reduced, pin prick and temperature reduced
reflexes- absent

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7
Q

what is the power, sensation and reflexes like for small fibre nerve damage?

A

power- normal
sensation- pin prick and temperature reduced
reflexes- present

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8
Q

what is the power, sensation and reflexes like for autonomic nerve damage?

A

power- normal
sensation-normal
reflexes- present

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9
Q

what in the nerve must be damaged for plexopathy?

A

plexus of nerve

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10
Q

what in the nerve must be damaged radiculopathy/ ganglionopathy?

A

ganglion?

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11
Q

what nerve damage does this suggest

A

median nerve damage (carpal tunnel)

-wasting of thenar eminence

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12
Q

damage to what nerves cause wrist drop and foot drop

A

wrist drop- radial
foot drop- common peroneal

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13
Q

common causes of axonal neuropathies?

A
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14
Q

common causes of peripheral demyelenation damage to nerves?

A

usually acute but can also be chronic

examples:
Guillain-Barre syndrome (acute)
CIDP (chronic inflammatory demyelinating polyradiculopathy)

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15
Q

how to tell the difference between axonal and demyelenation damage to nerves?

A

Do electrical studies (sensory and motor)
-demyelenation will take longer to due damage to myelin sheath

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16
Q

example of acute demyelinating neuropathy?

A

-Guillaine Barre syndrome
-AIDP

17
Q

example of chronic demyelinating neuropathy?

A

-CIPD (chronic inflammatory demyelinating polyradiculopathy)
-Hereditary sensory motor neuropathy (charcot marie tooth disease)

18
Q

treatment of axonal peripheral neuropathy?

A

-treat cause (ie clear hepatitis C)
-symptomatic relief (physio, orthotics, neuropathic pain relief)

19
Q

treatment of axonal (vasculitic) peripheral neuropathy?

A

Pulsed IV methylprednisolone + cyclophosphamide

20
Q

treatment of demyelinating (inflammatory neuropathy) peripheral neuropathy?

A

-IVIg (pooled immunoglobulin from donors)
-steroids
-azathioprine, mycophenalate, cyclophosphamide