Peripheral Nerves

Question 1

Free Nerve Endings (2 of them)

Answer 1

C fibers - slow, unmyelinated. Do dull pain/burning/itch/warm thermoRs
Adelta fibers - fast, myelianted, do prickly pain and cold thermoRs

Question 2

Meissner Corpuscles

Answer 2

Large myelinated rapid superficial fibers on HAIRLESS skin for fine/light touch

Question 3

Pacinian Corpuscles

Answer 3

Onion-skin appearing large, myelinated rapid deep in deep skin/ligaments joints that do vibration and pressure

Question 4

Merkel discs

Answer 4

Melanocyte-looking large myelinated fibers that adapt slow superficial fibers in fingertips for deep static touch and shit

Question 5

Ruffini corpuscles

Answer 5

Dendritic endings that are slow deep that do pressure and slippage and joint angles

Question 6

Proprioception Muscle Length vs. Tension

Answer 6

Muscle spindle vs. golgi tendon

Question 7

Progressive Multifocal Leukoencephalopathy

Answer 7

Demyelination of CNS due to destruction of oligodendrocytes, associated with JC virus

Question 8

Metachromatic Leukodystrophy

Answer 8

AR lysosomal storage disease due to arylsufatase A deficiency which leads to buildup of sulfatides and demyelination

Question 9

Krabbe Disease

Answer 9

AR lysosomal storage disease due to deficiency of galactocerebrosidase causing buildup of galactocerebroside and demyelination

Question 10

Charcot-Marie-Tooth Disease

Answer 10

Group of progressive hereditary nerve disorders lose peripheral n./myelination function and touch and foot stuff

Question 11

Acute Disseminated (postinfectious) Encephalomyelitis

Answer 11

Multifocal periventricular inflammation and demyelination after infection (measles or VZV) or vaccinations (rabies, smallpox)