Peptide Bond Flashcards

1
Q

its reactions is between amino group of one amino acid and carboxyl group of another amino acid.

A

Peptide Bond

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2
Q

Covalent bonds between amino acids in a peptide are called

A

peptide bonds (amide).

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3
Q

bonds between amino acids in a peptide are called
peptide bonds (amide).

A

Covalent bonds

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4
Q

The structure of peptides is represented beginning with the amino acid whose
amino group is free

A

(N-terminal end).

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5
Q

The other end contains a free carboxyl
group and is the

A

C-terminal end

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6
Q

amino acids are added to a peptide by forming

A

peptide bonds

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7
Q

are added to a peptide by forming peptide bonds

A

amino acids

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8
Q

The peptide linkages are essentially

A

planar

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9
Q

the —– linkages are essentially planar

A

peptide linkages

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10
Q

The planar peptide linkage structure has considerable

A

rigidity

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11
Q

a peptide linkage structure has considerable rigidity

A

planar peptide linkage

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12
Q

3 Many relatively small peptides are biochemically active

A
  • Neurotransmitters
  • Hormones
  • Antioxidants
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13
Q

2 Best-known peptide hormones:

A

oxytocin and vasopressin

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14
Q

Produced by the pituitary gland

A

Peptide Hormones:

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15
Q

Peptide Hormones are produced by the

A

pituitary gland

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16
Q

(nine amino acid residues)

A

Nona-peptide

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17
Q

Nona-peptide (nine amino acid residues) with six of the residues
held in the form of a loop by a

A

disulfide bond

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18
Q

Nona-peptide (nine amino acid residues) with six of the residues held in the form of a loop by a disulfide bond formed between two

A

cysteine residues

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19
Q

Known for its role in social bonding, sexual reproduction,
childbirth, and post-childbirth.

A

Oxytocin:

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20
Q

It has Isoleucine (Ile) at position 3 and Leucine (Leu) at position

21
Q

in oxytocin where is the position of the isoleucine

A

position 3

22
Q

in oxytocin where is the position of the leucine

A

position 8

23
Q

Involved in water retention in the kidneys and regulation of blood pressure.

A

Vasopressin:

24
Q

It has Isoleucine (Ile) at position 3 and Leucine (Leu) at position 8

25
It has Phenylalanine (Phe) at position 3 and Arginine (Arg) at position 8.
Vasopressin:
26
in Vasopressin, it has phenylalanine at
position 3
27
in Vasopressin, it has arginine at
position 8
28
3 Biochemically Important Small Peptides
Enkephalin Glutathione Aspartame
29
are penta-peptide neurotransmitters produced by the brain and they bind to opioid receptors,
Enkephalin
30
which are involved in pain regulation and reward systems.
Enkephalin
31
Associated with euphoria and addiction.
Enkephalin
32
Enkephalin is associated with
euphoria and addiction
33
Help reduce pain
Enkephalin
34
Best-known enkephalins:
Enkephalin
35
Met-enkephalin:
Tyr–Gly–Gly–Phe–Met
36
Tyr–Gly–Gly–Phe–Met
Met-enkephalin:
37
Leu-enkephalin:
Tyr–Gly–Gly–Phe–Leu
38
Tyr–Gly–Gly–Phe–Leu
Leu-enkephalin:
39
(Glu–Cys–Gly)
Glutathione
40
a tri-peptide – present in high levels in most cells.
Glutathione
41
Regulator of oxidation–reduction reactions.
Glutathione
42
is an antioxidant and protects cellular contents from oxidizing agents such as peroxides and superoxide
Glutathione
43
Glutathione is an antioxidant and protects cellular contents from oxidizing agents such as ---- and ----
peroxides and superoxide
44
Highly reactive forms of oxygen often generated within the cell in response to bacterial invasion
peroxides and superoxide
45
(Asp-Phe)
Aspartame
46
di-peptide that act as artificial sweeteners
Aspartame
47
180x as sweet as sucrose
Aspartame
48
Aspartame is 180x as sweet as
sucrose
49
Glutathione is a regulator of ---------------- reactions
oxidation–reduction reactions.