Pemphigoid Flashcards
1
Q
What population group usually get pemphigoid?
A
The elderly (60 years plus)
2
Q
Do the blister heal with or without scarring?
A
Without scarring
3
Q
What causes pemphigoid?
A
IgG autoantibodies against basement membrane
4
Q
What level does the blistering occur at?
A
The Subepidermal level.
- (Deeper than in pemiphus vulagris which is at the dermal-epidermal junction)
- Also why in pemphigoid they are tense whilst in PV they burst.
5
Q
How do you differentiate PV for pemphigoid?
A
Skin biopsy for routine and direct immunofluorescence