Acanthosis Nigrans Flashcards
1
Q
What are some causes of acanthosis nigrans?
A
- Gastrointestinal cancer
- Diabetes mellitus
- Obesity
- Polycystic ovarian syndrome
- Acromegaly
- Cushing’s disease
- Hypothyroidism
- Familial
- Prader-Willi syndrome
- Drugs: oral contraceptive pill, nicotinic acid
2
Q
A
3
Q
If acanthosis nigrans develops rapidly and in an atypical location (e.g. oral cavity), what should be suspected?
A
An interntal malignancy - in particular Gastric/GI cancer.
4
Q
What skin types is acanthosis nigrans more likely to occur in with no particular cause?
A
Dark skinned individuals
5
Q
What can acanthosis nigrans indicate?
A
Insulin resistance and related conditions.
- T2DM
- PCOS
- Cushings syndrome
- obesity
- hypothyroidism
- Acromegaly
- Prader-Willi (prone to diabetes)
6
Q
What drugs can cause acanthosis nigrans?
A
- Corticosteroids
- Insulin
- Hormone medication (COCP)
- Nicotinic acid.
