Pegaptanib Flashcards
1
Q
MOA
A
- Attached polyethylene glycol to drug molecule
- Decreases antigenicity
- Increases molecular size to decrease renal clearance
- Increases water solubility
2
Q
Indications
A
Wet AMD
3
Q
Warning/precautions
A
Pregnancy category B
4
Q
Adverse reactions
A
- Endophthalmitis and increased IOP after injection
- Blepharitis
- Conjunctivitis
- Photopsia
- Bronchitis
- Diarrhea, dizziness, headache, nausea, UTI
5
Q
Brand name
A
Macugen