Alpha Agonists Flashcards
1
Q
1st Generation
A
Apraclonidine (Iopidine)
2
Q
2nd Generation
A
- Brimonidine (Alphagan P)
- Brimonidine, timolol (Combigan)
3
Q
MOA
A
Improves aqueous humor outflow
4
Q
Indications
A
- 2nd line for glaucoma
- Decrease IOP by 20-25%
5
Q
Contraindications
A
- Patients taking MAO inhibitors (they interact with everything)
- Kids under 2 y/o
6
Q
Adverse reactions
A
- Conjunctival injection (10 to 20%)
- Hyperemia, itching (10-20%)
- Vision change
- Fatigue, somnolence
- Headache