Alpha Agonists Flashcards

1
Q

1st Generation

A

Apraclonidine (Iopidine)

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2
Q

2nd Generation

A
  • Brimonidine (Alphagan P)

- Brimonidine, timolol (Combigan)

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3
Q

MOA

A

Improves aqueous humor outflow

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4
Q

Indications

A
  • 2nd line for glaucoma

- Decrease IOP by 20-25%

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5
Q

Contraindications

A
  • Patients taking MAO inhibitors (they interact with everything)
  • Kids under 2 y/o
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6
Q

Adverse reactions

A
  • Conjunctival injection (10 to 20%)
  • Hyperemia, itching (10-20%)
  • Vision change
  • Fatigue, somnolence
  • Headache
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