Pediatric Pulmonology Flashcards
What is chronic inflammatory disorder that produces airway hyperresponsiveness, airflow limitation and persistent respiratory symtpoms
Asthma
what is the strongest predisposing factor for asthma
atopy
what is the first line medication treatment for asthma
short-acting beta agonist as needed
What is status asthmaticus
medical emergency that requires careful evaluation and agressive therapy - asthma attack refratory to treatment
what is the mainstay of medical therapy for status asthmaticus
frequent administration of beta-agonists inhalations, combined with early corticosteroid use
IV magnesium can be used as an adjunctive measure
THeohylline may be also used as an adjunctive measure
may hae to consider mechanical ventilation
what is the leading cause of death in children with asthma
hypoxia
what are the indications for ICU admission with status asthmaticus
altered sensorium
use of continuous inhaled beta-agonist therapy
exhaustion
markedly decreased air entry
rising PCO2 despite treatment
prescence of high-risk factors for a severe attack
fialure to improve despite adequate therapy
What is cystic fibrosis
autosomal recessive inherited disorder
progressive dysfunction of ion channel responsible for movement of water and salt through epithelail cells
thick viscous mucus builds up, ccompromises host defenses
what is the classic presentation of CF
toddler to small child with bronchiectasis, pancreatic insufficiency, growth delays (aka failure to thrive) and infertility
what is the pulmonary presentation of CF
persistent cough, productive due to hypersecretion
pulmonary inflam, obstruction
wheezing, dyspnea
recurrent infection
what is the liver presentation with CF
hepatic insufficiency
prolonged neonatal jaundice
what is the pancreatic presentation with CF
pancreatic insufficiency
steatorrhea
malabsorption
pnacreatitis
exocrine hypersecretion
how is CF diagnosed/worked up
newborn screen may include immunoreactice trypsin (IRT) measurement, elevated with CF
sweat chloride test
confirmation via genetic testing (definitive)
what is the gold standard for diagnosis of CF
sweat chloride testing
what is the treatment of pneumonia
broad spectrum abx for severely ill pts
oral abx for less severe (cefuroxime, amox, augmentin, macrolide)