Pediatric Neurology Flashcards
when in the incidence of seizures greatest during childhood
neonatal (birth to 8 weeks of life)
what is an abnormal, synchronous electrical activity of neurons in the cerebral cortex
seizure
what are causes if seizures in children
usu. d/t acute illness/injuyr:
electrical abnormalities
ingestion of toxins
trauma/intracranial bleeding
meningitis
fever
is a seizure in a child diagnostic for epilepsy
no
epilepsy is recurrent, unprovoked seizures
How are seizures classified
generalized onset
focal onset (partial)
unknown onset
unclassified
What are the types of generalized seizures
motor (convulsive) and non-motor (nonconvulsive, absence)
what are the types of motor (convulsive) seizure
tonic-clonic: m/c
clonic
tonic
myoclonic
atonic (“drop attacks”)
what are the types of non-motor seizures
typical
atypical
myoclonic
eyelid myoclonic
What are focal seizures
limited to one hemisphere
1. intact awareness (simple partial seizure)
2. impaired awareness (complex partial seizure)
what. isa complex partial seizure
focal onset seizure with impaired awareness
what. isa simple partial seizure
focal onset seizure with intact awareness
what is Jacksonian March
Start as a focal seizure but progress to a generalized seizure
what is a condition that is characterized by recurrent (2+) seizures, unprovoked by any immediate identified causes, > 24 hours apart
Epilepsy
What is. themost common seizure disorder of childhood
generalized non-motor absence seizure
what is the median onset of age for absence seizures
6 years old
most present between 4-10 years old
what is a typical absence seizure
brief loss of awareness, staring, eye fluttering; head bobbing/lip smacking
lasts < 10 seconds
can be provoked by hyperventilation
what is a atypical absence seizure
head atony (“drop attack of the head”)
What is the treatment of absence seizures
Zarontin (ethosuximide) 250 PO BID - first line
valproic acid or Lamotrigine(lamictal)
children with typical absence seizures may need to be on medications for
(atypical need lifelong treatment)
What is SUDEP
Sudden unexpected death in Epilepsy
sudden, unexpected, non-traumatic, non-drowning death, no structural or toxicologic cause
what is the evaluation of the first afebrile seizure
ABCs
History
fundoscopic exam
neurologic exam
cardiac
skin exam
what skin disorders can be associated with epilepsy
tuberous sclerosis
neurofibromatosis
Sturge Weber syndrome
what is Sturge Weber syndrome
port wine stain
vascular malformations
seizures
focal neuro deficits
cognitive impairment
what is Tuberous Sclerosis
ash-leaf spots, angiofibroma’s, fibrous plaques, shagreen patch
what post seizure labs should be ordered
glucose
electrolytes, including mag and calcium
consider tox screening
what is the imaging test of choice for afebrile seizures
MRI
CT is often the first study in the ED
are antiepileptic medications started after the first seizure?
Not routinely, the decision to start medication should be made with great care
what is the most common neurologic disorder in infants and children
Febrile seizures
when are febrile seizures most common to occur
on the first day of the illness
may be presenting sign of illness, can present with status epilepticus
what are the criteria for febrile seizure
seizure activity associated with elevated temp (>100.4)
child 6 mo - 6 years
NO CNS infxn/inflam
NO acute systemic metabolic abnormality that may produce convulsions
NO hx of previous afebrile seizure
what are the types of Febrile seizures?
Simple febrile (M/C)
Complex Febrile