PCSK9 inhibitors Flashcards
1
Q
Prototype
A
Alirocumab
2
Q
Route
A
SQ every 2 weeks
3
Q
Metabolized
A
into small peptides and amino acids
4
Q
Eliminated
A
proteolysis
5
Q
Action
A
Prolong activity of the receptors that clear cholesterol
6
Q
Use
A
Hypercholesterolemia when diet and statins are not effective
7
Q
Adverse effects
A
injection site reaction
nasopharyngitis
muscle pain
itching
influenza
diarrhea
allergic reaction
8
Q
Interactions
A
None
9
Q
Contraindications
A
hypersensitivity
