Immunosuppressant Monoclonal antibodies Flashcards

1
Q

Prototype

A

omalizumab

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2
Q

Route

A

SQ

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3
Q

pharmacokinetics

A

slow absorption

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4
Q

excreted

A

liver

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5
Q

metabolized

A

liver

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6
Q

Action

A

Inhibits IgE binding which limits activation and release of mediators of allergic response

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7
Q

Adverse effects

A

local reaction
headache
fatigue
nausea
Black box warning for anaphylaxis

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