Nicotinic Acid Flashcards
1
Q
Prototype
A
miscellaneous dyslipidemia agent
Niacin (VB3)
2
Q
Route
A
PO
3
Q
Pharmacokinetics
A
rapidly absorbed
4
Q
Metabolized
A
minimal in liver
5
Q
Excreted
A
Mostly unchanged in the liver
6
Q
Action
A
Decreases hepatic synthesis of triglycerides, decreased production of LDL, increases HDL levels
7
Q
Use
A
Works in conjunction with bile acid sequestrant or fibrate
8
Q
Adverse effects
A
Flushing
Pruritis
Tachycardia
Hypotension
Dizziness
9
Q
Interactions
A
increases risk of myopathy with statins
Decreases efficacy of oral hypoglycemic agents
10
Q
Contraindications
A
active hepatic disease
Active peptic ulcer
