Diuretics Flashcards
Types of diuretics
Osmotic, thiazide, potassium-sparing, loop
Prototype of osmotic diuretics
Mannitol
Prototype of Thiazide diuretics
Hydrochlorothiazide
Thiazide diuretics Work on which area of the nephron
distal tubule
Thiazide diuretics
What is the mechanism of action
Decreases the reabsorption of sodium
water and sodium follow each other
What is one of the main uses of thiazide diuretics
High blood pressure
Side effect of thiazide diuretics
Hypotension, electrolyte disturbance, erectile dysfunction
Prototype of Potassium-sparing diuretics
Spironolactone
Potassium-sparing Work on which area of the nephron
distal tubule
Potassium-sparing cause Large or small amount of diuresis
small
Side effects of potassium-sparing
Dizziness, androgen receptor stimulation (voice deeper, breast tissue), tumorigenic, hyperkalemia
What does is mean if something is tumorigenic
Can cause tumor growth
Potassium-sparing are tumorigenic
Prototype of loop diuretics
Furosemide
loop diuretics work on which area of the nephron
the loop
How much diuresis with loop diuretics
large